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ERRα Regulated Lactate Metabolism Contributes to Resistance to Targeted Therapies in Breast Cancer

Imaging studies in animals and in humans have indicated that the oxygenation and nutritional status of solid tumors is dynamic. Further, the extremely low level of glucose within tumors, while reflecting its rapid uptake and metabolism, also suggests that cancer cells must rely on other energy sourc...

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Bibliografiska uppgifter
I publikationen:Cell Rep
Huvudupphovsmän: Park, Sunghee, Chang, Ching-yi, Safi, Rachid, Liu, Xiaojing, Baldi, Robert, Jasper, Jeff S., Anderson, Grace R., Liu, Tingyu, Rathmell, Jeffrey C., Dewhirst, Mark W., Wood, Kris C., Locasale, Jason W., McDonnell, Donald P.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833658/
https://ncbi.nlm.nih.gov/pubmed/27050525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.03.026
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