ERRα Regulated Lactate Metabolism Contributes to Resistance to Targeted Therapies in Breast Cancer

Imaging studies in animals and in humans have indicated that the oxygenation and nutritional status of solid tumors is dynamic. Further, the extremely low level of glucose within tumors, while reflecting its rapid uptake and metabolism, also suggests that cancer cells must rely on other energy sourc...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Park, Sunghee, Chang, Ching-yi, Safi, Rachid, Liu, Xiaojing, Baldi, Robert, Jasper, Jeff S., Anderson, Grace R., Liu, Tingyu, Rathmell, Jeffrey C., Dewhirst, Mark W., Wood, Kris C., Locasale, Jason W., McDonnell, Donald P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833658/
https://ncbi.nlm.nih.gov/pubmed/27050525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.03.026
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