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The metabolic regulator ERRα, a downstream target of HER2/IGF-1, as a therapeutic target in breast cancer

A genomic signature designed to assess the activity of the estrogen-related receptor alpha (ERRα) was used to profile more than eight hundred breast tumors, revealing a shorter disease-free survival in patients with tumors exhibiting elevated receptor activity. Importantly, this signature also predi...

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Detalhes bibliográficos
Main Authors: Chang, Ching-yi, Kazmin, Dmitri, Jasper, Jeff S., Kunder, Rebecca, Zuercher, William J., McDonnell, Donald P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199323/
https://ncbi.nlm.nih.gov/pubmed/22014575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2011.08.023
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