INVESTIGATIONS INTO TROPOMYOSIN FUNCTION USING MOUSE MODELS

অনুযায়ী Jagatheesan, Ganapathy, Rajan, Sudarsan, Wieczorek, David F.
প্রকাশিত 2009

Identification of two new regions in the N-terminus of cardiac troponin T that have divergent effects on cardiac contractile function

অনুযায়ী Mamidi, Ranganath, Mallampalli, Sri Lakshmi, Wieczorek, David F, Chandra, Murali
প্রকাশিত 2013

N-acetylcysteine reverses diastolic dysfunction and hypertrophy in familial hypertrophic cardiomyopathy

অনুযায়ী Wilder, Tanganyika, Ryba, David M., Wieczorek, David F., Wolska, Beata M., Solaro, R. John
প্রকাশিত Am J Physiol Heart Circ Physiol (2015)

Microarray analysis of active cardiac remodeling genes in a familial hypertrophic cardiomyopathy mouse model rescued by a phospholamban knockout

অনুযায়ী Rajan, Sudarsan, Pena, James R., Jegga, Anil G., Aronow, Bruce J., Wolska, Beata M., Wieczorek, David F.
প্রকাশিত 2013

Use of 2-D DIGE analysis reveals altered phosphorylation in a tropomyosin mutant (Glu54Lys) linked to dilated cardiomyopathy

অনুযায়ী Warren, Chad M., Arteaga, Grace M., Rajan, Sudarsan, Ahmed, Rafeeq P. H., Wieczorek, David F., Solaro, R. John
প্রকাশিত 2008

Expression of tropomyosin-κ induces dilated cardiomyopathy and depresses cardiac myofilament tension by mechanisms involving cross-bridge dependent activation and altered tropomyos...

অনুযায়ী Karam, Chehade N., Warren, Chad M., Rajan, Sudarsan, de Tombe, Pieter P., Wieczorek, David F., Solaro, R. John
প্রকাশিত 2011

Decreasing Tropomyosin Phosphorylation Rescues Tropomyosin-induced Familial Hypertrophic Cardiomyopathy

অনুযায়ী Schulz, Emily M., Wilder, Tanganyika, Chowdhury, Shamim A. K., Sheikh, Hajer N., Wolska, Beata M., Solaro, R. John, Wieczorek, David F.
প্রকাশিত 2013

Ceramide-mediated depression in cardiomyocyte contractility through PKC activation and modulation of myofilament protein phosphorylation

অনুযায়ী Simon, Jillian N., Chowdhury, Shamim A.K., Warren, Chad M., Sadayappan, Sakthivel, Wieczorek, David F., Solaro, R. John, Wolska, Beata M.
প্রকাশিত Basic Res Cardiol (2014)

Functional effects of a tropomyosin mutation linked to FHC contribute to maladaptation during acidosis

অনুযায়ী Sheehan, Katherine A., Arteaga, Grace M., Hinken, Aaron C., Dias, Fernando A., Ribeiro, Cibele, Wieczorek, David F., Solaro, R. John, Wolska, Beata M.
প্রকাশিত 2010

Expression of a novel tropomyosin isoform in axolotl heart and skeletal muscle

অনুযায়ী Thomas, Anish, Rajan, Sudarsan, Thurston, Harold L., Masineni, Sreeharsha N., Dube, Preeti, Bose, Abhishek, Muthu, Vasundhara, Dube, Syamalima, Wieczorek, David F., Dube, Dipak K.
প্রকাশিত 2010

Cardiac myosin light chain phosphorylation and inotropic effects of a biased ligand, TRV120023, in a dilated cardiomyopathy model

অনুযায়ী Tarigopula, Madhusudhan, Davis, Robert T., Mungai, Paul T., Ryba, David M., Wieczorek, David F., Cowan, Conrad L., Violin, Jonathan D., Wolska, Beata M., Solaro, R. John
প্রকাশিত Cardiovasc Res (2015)

Early sensitization of myofilaments to Ca(2+) prevents genetically linked dilated cardiomyopathy in mice

অনুযায়ী Alves, Marco L., Warren, Chad M., Simon, Jillian N., Gaffin, Robert D., Montminy, Eric M., Wieczorek, David F., Solaro, R. John, Wolska, Beata M.
প্রকাশিত Cardiovasc Res (2017)

Tropomyosin pseudo-phosphorylation results in dilated cardiomyopathy

অনুযায়ী Rajan, Sudarsan, Jagatheesan, Ganapathy, Petrashevskaya, Natalia, Biesiadecki, Brandon J., Warren, Chad M., Riddle, Tara, Liggett, Stephen, Wolska, Beata M., Solaro, R. John, Wieczorek, David F.
প্রকাশিত J Biol Chem (2019)

Effects of nicotine administration in a mouse model of familial hypertrophic cardiomyopathy, α-tropomyosin D175N

অনুযায়ী Gaffin, Robert D., Chowdhury, Shamim A. K., Alves, Marco S. L., Dias, Fernando A. L., Ribeiro, Cibele T. D., Fogaca, Rosalvo T. H., Wieczorek, David F., Wolska, Beata M.
প্রকাশিত 2011

Striated muscle tropomyosin isoforms differentially regulate cardiac performance and myofilament calcium sensitivity

অনুযায়ী Jagatheesan, Ganapathy, Rajan, Sudarsan, Ahmed, Rafeeq P. H., Petrashevskaya, Natalia, Boivin, Greg, Arteaga, Grace M., Tae, Hyun-Jin, Liggett, Stephen B., Solaro, R. John, Wieczorek, David F.
প্রকাশিত 2010

Conserved Asp-137 Is Important for both Structure and Regulatory Functions of Cardiac α-Tropomyosin (α-TM) in a Novel Transgenic Mouse Model Expressing α-TM-D137L

অনুযায়ী Yar, Sumeyye, Chowdhury, Shamim A. K., Davis, Robert T., Kobayashi, Minae, Monasky, Michelle M., Rajan, Sudarsan, Wolska, Beata M., Gaponenko, Vadim, Kobayashi, Tomoyoshi, Wieczorek, David F., Solaro, R. John
প্রকাশিত 2013

Loss of the AE3 Anion Exchanger in a Hypertrophic Cardiomyopathy Model Causes Rapid Decompensation and Heart Failure

অনুযায়ী Al Moamen, Nabeel J., Prasad, Vikram, Bodi, Ilona, Miller, Marian L., Neiman, Michelle L., Lasko, Valerie M., Alper, Seth L., Wieczorek, David F., Lorenz, John N., Shull, Gary E.
প্রকাশিত 2010

Long-term Rescue of a Familial Hypertrophic Cardiomyopathy Caused by a Mutation in the Thin Filament Protein, Tropomyosin, via Modulation of a Calcium Cycling Protein

অনুযায়ী Gaffin, Robert D, Peña, James R, Alves, Marco S L, Dias, Fernando A L, Chowdhury, Shamim, Heinrich, Lynley S, Goldspink, Paul H, Kranias, Evangelia G, Wieczorek, David F, Wolska, Beata M
প্রকাশিত 2011

Neonatal Gene Transfer of Serca2a Delays Onset of Hypertrophic Remodeling and Improves Function in Familial Hypertrophic Cardiomyopathy

অনুযায়ী Peña, James R, Szkudlarek, Ariani C, Warren, Chad, Heinrich, Lynley S, Gaffin, Robert D., Jagatheesan, Ganapathy, del Monte, Federica, Hajjar, Roger J, Goldspink, Paul H, Solaro, R. John, Wieczorek, David F, Wolska, Beata M
প্রকাশিত 2010

Tropomyosin Dephosphorylation Results in Compensated Cardiac Hypertrophy

অনুযায়ী Schulz, Emily M., Correll, Richard N., Sheikh, Hajer N., Lofrano-Alves, Marco S., Engel, Patti L., Newman, Gilbert, Schultz, Jo El J., Molkentin, Jeffery D., Wolska, Beata M., Solaro, R. John, Wieczorek, David F.
প্রকাশিত 2012