Neonatal Gene Transfer of Serca2a Delays Onset of Hypertrophic Remodeling and Improves Function in Familial Hypertrophic Cardiomyopathy

Familial Hypertrophic Cardiomyopathy (FHC) is an autosomal dominant genetic disorder linked to numerous mutations in the sarcomeric proteins. The clinical presentation of FHC is highly variable, but it is a major cause of sudden cardiac death in young adults with no specific treatments. We tested th...

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Autores principales: Peña, James R, Szkudlarek, Ariani C, Warren, Chad, Heinrich, Lynley S, Gaffin, Robert D., Jagatheesan, Ganapathy, del Monte, Federica, Hajjar, Roger J, Goldspink, Paul H, Solaro, R. John, Wieczorek, David F, Wolska, Beata M
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2982190/
https://ncbi.nlm.nih.gov/pubmed/20854827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2010.09.010
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