Compromised redox homeostasis, altered nitroso–redox balance, and therapeutic possibilities in atrial fibrillation

por Simon, Jillian N., Ziberna, Klemen, Casadei, Barbara
Publicado en Cardiovasc Res (2016)

Oxidation resistance 1 regulates post-translational modifications of peroxiredoxin 2 in the cerebellum

por Svistunova, Daria M., Simon, Jillian N., Rembeza, Elzbieta, Crabtree, Mark, Yue, Wyatt W., Oliver, Peter L., Finelli, Mattéa J.
Publicado en Free Radic Biol Med (2018)

Ceramide-mediated depression in cardiomyocyte contractility through PKC activation and modulation of myofilament protein phosphorylation

por Simon, Jillian N., Chowdhury, Shamim A.K., Warren, Chad M., Sadayappan, Sakthivel, Wieczorek, David F., Solaro, R. John, Wolska, Beata M.
Publicado en Basic Res Cardiol (2014)

Early sensitization of myofilaments to Ca(2+) prevents genetically linked dilated cardiomyopathy in mice

por Alves, Marco L., Warren, Chad M., Simon, Jillian N., Gaffin, Robert D., Montminy, Eric M., Wieczorek, David F., Solaro, R. John, Wolska, Beata M.
Publicado en Cardiovasc Res (2017)

The subcellular localization of neuronal nitric oxide synthase determines the downstream effects of NO on myocardial function

por Carnicer, Ricardo, Suffredini, Silvia, Liu, Xing, Reilly, Svetlana, Simon, Jillian N., Surdo, Nicoletta C., Zhang, Yin H., Lygate, Craig A., Channon, Keith M., Casadei, Barbara
Publicado en Cardiovasc Res (2017)

Knockout of p21-activated kinase-1 attenuates exercise-induced cardiac remodelling through altered calcineurin signalling

por Davis, Robert T., Simon, Jillian N., Utter, Megan, Mungai, Paul, Alvarez, Manuel G., Chowdhury, Shamim A.K., Heydemann, Ahlke, Ke, Yunbo, Wolska, Beata M., Solaro, R. John
Publicado en Cardiovasc Res (2015)

Nitric oxide modulates cardiomyocyte pH control through a biphasic effect on sodium/hydrogen exchanger-1

por Richards, Mark A, Simon, Jillian N, Ma, Ruichong, Loonat, Aminah A, Crabtree, Mark J, Paterson, David J, Fahlman, Richard P, Casadei, Barbara, Fliegel, Larry, Swietach, Pawel
Publicado en Cardiovasc Res (2019)

Modifications of Sarcoplasmic Reticulum Function Prevent Progression of Sarcomere-Linked Hypertrophic Cardiomyopathy Despite a Persistent Increase in Myofilament Calcium Response

por Chowdhury, Shamim A. K., Warren, Chad M., Simon, Jillian N., Ryba, David M., Batra, Ashley, Varga, Peter, Kranias, Evangelia G., Tardiff, Jil C., Solaro, R. John, Wolska, Beata M.
Publicado en Front Physiol (2020)

BH4 Increases nNOS Activity and Preserves Left Ventricular Function in Diabetes

por Carnicer, Ricardo, Duglan, Drew, Ziberna, Klemen, Recalde, Alice, Reilly, Svetlana, Simon, Jillian N., Mafrici, Simona, Arya, Ritu, Rosello-Lleti, Esther, Chuaiphichai, Surawee, Tyler, Damian, Lygate, Craig A., Channon, Keith M., Casadei, Barbara
Publicado en Circ Res (2021)

Impaired cardiac contractile function in arginine:glycine amidinotransferase knockout mice devoid of creatine is rescued by homoarginine but not creatine

por Faller, Kiterie M E, Atzler, Dorothee, McAndrew, Debra J, Zervou, Sevasti, Whittington, Hannah J, Simon, Jillian N, Aksentijevic, Dunja, ten Hove, Michiel, Choe, Chi-un, Isbrandt, Dirk, Casadei, Barbara, Schneider, Jurgen E, Neubauer, Stefan, Lygate, Craig A
Publicado en Cardiovasc Res (2018)

Oxidation of Protein Kinase A Regulatory Subunit PKARIα Protects Against Myocardial Ischemia-Reperfusion Injury by Inhibiting Lysosomal-Triggered Calcium Release

por Simon, Jillian N., Vrellaku, Besarte, Monterisi, Stefania, Chu, Sandy M., Rawlings, Nadiia, Lomas, Oliver, Marchal, Gerard A., Waithe, Dominic, Syeda, Fahima, Gajendragadkar, Parag R., Jayaram, Raja, Sayeed, Rana, Channon, Keith M., Fabritz, Larissa, Swietach, Pawel, Zaccolo, Manuela, Eaton, Philip, Casadei, Barbara
Publicado en Circulation (2020)

Desensitization of Myofilaments to Ca(2+) as a Therapeutic Target for Hypertrophic Cardiomyopathy with Mutations in Thin Filament Proteins

por Alves, Marco L., Dias, Fernando A.L., Gaffin, Robert D., Simon, Jillian N., Montminy, Eric M., Biesiadecki, Brandon J., Hinken, Aaron C., Warren, Chad M., Utter, Megan S., Davis, Robert T., Sakthivel, Sadayappan, Robbins, Jeffrey, Wieczorek, David F., Solaro, R. John, Wolska, Beata M.
Publicado 2014

Functional analysis of a gene-edited mouse model to gain insights into the disease mechanisms of a titin missense variant

por Jiang, He, Hooper, Charlotte, Kelly, Matthew, Steeples, Violetta, Simon, Jillian N., Beglov, Julia, Azad, Amar J., Leinhos, Lisa, Bennett, Pauline, Ehler, Elisabeth, Kalisch-Smith, Jacinta I., Sparrow, Duncan B., Fischer, Roman, Heilig, Raphael, Isackson, Henrik, Ehsan, Mehroz, Patone, Giannino, Huebner, Norbert, Davies, Benjamin, Watkins, Hugh, Gehmlich, Katja
Publicado en Basic Res Cardiol (2021)