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Knockout of p21-activated kinase-1 attenuates exercise-induced cardiac remodelling through altered calcineurin signalling

AIMS: Despite its known cardiovascular benefits, the intracellular signalling mechanisms underlying physiological cardiac growth remain poorly understood. Therefore, the purpose of this study was to investigate a novel role of p21-activated kinase-1 (Pak1) in the regulation of exercise-induced cardi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cardiovasc Res
Hauptverfasser: Davis, Robert T., Simon, Jillian N., Utter, Megan, Mungai, Paul, Alvarez, Manuel G., Chowdhury, Shamim A.K., Heydemann, Ahlke, Ke, Yunbo, Wolska, Beata M., Solaro, R. John
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648200/
https://ncbi.nlm.nih.gov/pubmed/26464331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvv234
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