Non-sarcomeric causes of heart failure

por Gehmlich, Katja, Ehler, Elisabeth
Publicado en Biophys Rev (2018)

Cyclin B degradation leads to NuMA release from dynein/dynactin and from spindle poles

por Gehmlich, Katja, Haren, Laurence, Merdes, Andreas
Publicado 2004

Genetics of and pathogenic mechanisms in arrhythmogenic right ventricular cardiomyopathy

por Vimalanathan, Anita Kiran, Ehler, Elisabeth, Gehmlich, Katja
Publicado en Biophys Rev (2018)

The Role of Z-disc Proteins in Myopathy and Cardiomyopathy

por Wadmore, Kirsty, Azad, Amar J., Gehmlich, Katja
Publicado en Int J Mol Sci (2021)

Fluorescent PSC-Derived Cardiomyocyte Reporter Lines: Generation Approaches and Their Applications in Cardiovascular Medicine

por Sontayananon, Naeramit, Redwood, Charles, Davies, Benjamin, Gehmlich, Katja
Publicado en Biology (Basel) (2020)

Complex Relationship Between Cardiac Fibroblasts and Cardiomyocytes in Health and Disease

por Hall, Caitlin, Gehmlich, Katja, Denning, Chris, Pavlovic, Davor
Publicado en J Am Heart Assoc (2021)

When signalling goes wrong: pathogenic variants in structural and signalling proteins causing cardiomyopathies

por Ehsan, Mehroz, Jiang, He, L.Thomson, Kate, Gehmlich, Katja
Publicado en J Muscle Res Cell Motil (2017)

The giant titin: how to evaluate its role in cardiomyopathies

por Azad, Amar, Poloni, Giulia, Sontayananon, Naeramit, Jiang, He, Gehmlich, Katja
Publicado en J Muscle Res Cell Motil (2019)

Nitric Oxide and Mechano-Electrical Transduction in Cardiomyocytes

por Boycott, Hannah E., Nguyen, My-Nhan, Vrellaku, Besarte, Gehmlich, Katja, Robinson, Paul
Publicado en Front Physiol (2020)

A novel desmocollin-2 mutation reveals insights into the molecular link between desmosomes and gap junctions

por Gehmlich, Katja, Lambiase, Pier D., Asimaki, Angeliki, Ciaccio, Edward J., Ehler, Elisabeth, Syrris, Petros, Saffitz, Jeffrey E., McKenna, William J.
Publicado 2011

Novel missense mutations in exon 15 of desmoglein-2: Role of the intracellular cadherin segment in arrhythmogenic right ventricular cardiomyopathy?

por Gehmlich, Katja, Asimaki, Angeliki, Cahill, Thomas J., Ehler, Elisabeth, Syrris, Petros, Zachara, Elisabetta, Re, Federica, Avella, Andrea, Monserrat, Lorenzo, Saffitz, Jeffrey E., McKenna, William J.
Publicado 2010

Age- and strain-related aberrant Ca(2+) release is associated with sudden cardiac death in the ACTC E99K mouse model of hypertrophic cardiomyopathy

por Rowlands, Christina T., Owen, Thomas, Lawal, Saheed, Cao, Shuangyi, Pandey, Samata S., Yang, Hsiang-Yu, Song, Weihua, Wilkinson, Ross, Alvarez-Laviada, Anita, Gehmlich, Katja, Marston, Steven B., MacLeod, Kenneth T.
Publicado en Am J Physiol Heart Circ Physiol (2017)

Mechanistic insights into arrhythmogenic right ventricular cardiomyopathy caused by desmocollin-2 mutations

por Gehmlich, Katja, Syrris, Petros, Peskett, Emma, Evans, Alison, Ehler, Elisabeth, Asimaki, Angeliki, Anastasakis, Aris, Tsatsopoulou, Adalena, Vouliotis, Apostolos-Ilias, Stefanadis, Christodoulos, Saffitz, Jeffrey E., Protonotarios, Nikos, McKenna, William J.
Publicado 2011

MLP and CARP are linked to chronic PKCα signalling in dilated cardiomyopathy

por Lange, Stephan, Gehmlich, Katja, Lun, Alexander S., Blondelle, Jordan, Hooper, Charlotte, Dalton, Nancy D., Alvarez, Erika A., Zhang, Xiaoyu, Bang, Marie-Louise, Abassi, Yama A., dos Remedios, Cristobal G., Peterson, Kirk L., Chen, Ju, Ehler, Elisabeth
Publicado en Nat Commun (2016)

Aberrant developmental titin splicing and dysregulated sarcomere length in Thymosin β4 knockout mice

por Smart, Nicola, Riegler, Johannes, Turtle, Cameron W., Lygate, Craig A., McAndrew, Debra J., Gehmlich, Katja, Dubé, Karina N., Price, Anthony N., Muthurangu, Vivek, Taylor, Andrew M., Lythgoe, Mark F., Redwood, Charles, Riley, Paul R.
Publicado en J Mol Cell Cardiol (2017)

Mutant Muscle LIM Protein C58G causes cardiomyopathy through protein depletion

por Ehsan, Mehroz, Kelly, Matthew, Hooper, Charlotte, Yavari, Arash, Beglov, Julia, Bellahcene, Mohamed, Ghataorhe, Kirandeep, Poloni, Giulia, Goel, Anuj, Kyriakou, Theodosios, Fleischanderl, Karin, Ehler, Elisabeth, Makeyev, Eugene, Lange, Stephan, Ashrafian, Houman, Redwood, Charles, Davies, Benjamin, Watkins, Hugh, Gehmlich, Katja
Publicado en J Mol Cell Cardiol (2018)

HspB1 phosphorylation regulates its intramolecular dynamics and mechanosensitive molecular chaperone interaction with filamin C

por Collier, Miranda P., Alderson, T. Reid, de Villiers, Carin P., Nicholls, Daisy, Gastall, Heidi Y., Allison, Timothy M., Degiacomi, Matteo T., Jiang, He, Mlynek, Georg, Fürst, Dieter O., van der Ven, Peter F. M., Djinovic-Carugo, Kristina, Baldwin, Andrew J., Watkins, Hugh, Gehmlich, Katja, Benesch, Justin L. P.
Publicado en Sci Adv (2019)

Functional analysis of a gene-edited mouse model to gain insights into the disease mechanisms of a titin missense variant

por Jiang, He, Hooper, Charlotte, Kelly, Matthew, Steeples, Violetta, Simon, Jillian N., Beglov, Julia, Azad, Amar J., Leinhos, Lisa, Bennett, Pauline, Ehler, Elisabeth, Kalisch-Smith, Jacinta I., Sparrow, Duncan B., Fischer, Roman, Heilig, Raphael, Isackson, Henrik, Ehsan, Mehroz, Patone, Giannino, Huebner, Norbert, Davies, Benjamin, Watkins, Hugh, Gehmlich, Katja
Publicado en Basic Res Cardiol (2021)

Combination of Whole Genome Sequencing, Linkage, and Functional Studies Implicates a Missense Mutation in Titin as a Cause of Autosomal Dominant Cardiomyopathy With Features of Lef...

por Hastings, Robert, de Villiers, Carin P., Hooper, Charlotte, Ormondroyd, Liz, Pagnamenta, Alistair, Lise, Stefano, Salatino, Silvia, Knight, Samantha J.L., Taylor, Jenny C., Thomson, Kate L., Arnold, Linda, Chatziefthimiou, Spyros D., Konarev, Petr V., Wilmanns, Matthias, Ehler, Elisabeth, Ghisleni, Andrea, Gautel, Mathias, Blair, Edward, Watkins, Hugh, Gehmlich, Katja
Publicado en Circ Cardiovasc Genet (2016)

Mammalian γ2 AMPK regulates intrinsic heart rate

por Yavari, Arash, Bellahcene, Mohamed, Bucchi, Annalisa, Sirenko, Syevda, Pinter, Katalin, Herring, Neil, Jung, Julia J., Tarasov, Kirill V., Sharpe, Emily J., Wolfien, Markus, Czibik, Gabor, Steeples, Violetta, Ghaffari, Sahar, Nguyen, Chinh, Stockenhuber, Alexander, Clair, Joshua R. St., Rimmbach, Christian, Okamoto, Yosuke, Yang, Dongmei, Wang, Mingyi, Ziman, Bruce D., Moen, Jack M., Riordon, Daniel R., Ramirez, Christopher, Paina, Manuel, Lee, Joonho, Zhang, Jing, Ahmet, Ismayil, Matt, Michael G., Tarasova, Yelena S., Baban, Dilair, Sahgal, Natasha, Lockstone, Helen, Puliyadi, Rathi, de Bono, Joseph, Siggs, Owen M., Gomes, John, Muskett, Hannah, Maguire, Mahon L., Beglov, Youlia, Kelly, Matthew, dos Santos, Pedro P. N., Bright, Nicola J., Woods, Angela, Gehmlich, Katja, Isackson, Henrik, Douglas, Gillian, Ferguson, David J. P., Schneider, Jürgen E., Tinker, Andrew, Wolkenhauer, Olaf, Channon, Keith M., Cornall, Richard J., Sternick, Eduardo B., Paterson, David J., Redwood, Charles S., Carling, David, Proenza, Catherine, David, Robert, Baruscotti, Mirko, DiFrancesco, Dario, Lakatta, Edward G., Watkins, Hugh, Ashrafian, Houman
Publicado en Nat Commun (2017)