The genetic basis for inherited forms of sinoatrial dysfunction and atrioventricular node dysfunction

gan Milanesi, Raffaella, Bucchi, Annalisa, Baruscotti, Mirko
Cyhoeddwyd yn J Interv Card Electrophysiol (2015)

Current-dependent Block of Rabbit Sino-Atrial Node I(f) Channels by Ivabradine

gan Bucchi, Annalisa, Baruscotti, Mirko, DiFrancesco, Dario
Cyhoeddwyd 2002

Funny Current and Cardiac Rhythm: Insights from HCN Knockout and Transgenic Mouse Models

gan Bucchi, Annalisa, Barbuti, Andrea, DiFrancesco, Dario, Baruscotti, Mirko
Cyhoeddwyd 2012

Regulation of Gating and Rundown of HCN Hyperpolarization-activated Channels by Exogenous and Endogenous PIP(2)

gan Pian, Phillip, Bucchi, Annalisa, Robinson, Richard B., Siegelbaum, Steven A.
Cyhoeddwyd 2006

Integrated Allosteric Model of Voltage Gating of Hcn Channels

gan Altomare, Claudia, Bucchi, Annalisa, Camatini, Eva, Baruscotti, Mirko, Viscomi, Carlo, Moroni, Anna, DiFrancesco, Dario
Cyhoeddwyd 2001

Identification of the Molecular Site of Ivabradine Binding to HCN4 Channels

gan Bucchi, Annalisa, Baruscotti, Mirko, Nardini, Marco, Barbuti, Andrea, Micheloni, Stefano, Bolognesi, Martino, DiFrancesco, Dario
Cyhoeddwyd 2013

Age-Related Changes in Cardiac Autonomic Modulation and Heart Rate Variability in Mice

gan Piantoni, Chiara, Carnevali, Luca, Molla, David, Barbuti, Andrea, DiFrancesco, Dario, Bucchi, Annalisa, Baruscotti, Mirko
Cyhoeddwyd yn Front Neurosci (2021)

In vitro characterization of HCN channel kinetics and frequency dependence in myocytes predicts biological pacemaker functionality

gan Zhao, Xin, Bucchi, Annalisa, Oren, Ronit V, Kryukova, Yelena, Dun, Wen, Clancy, Colleen E, Robinson, Richard B
Cyhoeddwyd 2009

A detailed characterization of the hyperpolarization-activated “funny” current (I(f)) in human-induced pluripotent stem cell (iPSC)–derived cardiomyocytes with pacemaker activity...

gan Giannetti, Federica, Benzoni, Patrizia, Campostrini, Giulia, Milanesi, Raffaella, Bucchi, Annalisa, Baruscotti, Mirko, Dell’Era, Patrizia, Rossini, Alessandra, Barbuti, Andrea
Cyhoeddwyd yn Pflugers Arch (2021)

HCN212-channel biological pacemakers manifesting ventricular tachyarrhythmias are responsive to treatment with I(f) blockade

gan Plotnikov, Alexei N., Bucchi, Annalisa, Shlapakova, Iryna, Danilo, Peter, Brink, Peter R., Robinson, Richard B., Cohen, Ira S., Rosen, Michael R.
Cyhoeddwyd 2007

I(NaP) selective inhibition reverts precocious inter- and motorneurons hyperexcitability in the Sod1-G93R zebrafish ALS model

gan Benedetti, Lorena, Ghilardi, Anna, Rottoli, Elsa, De Maglie, Marcella, Prosperi, Laura, Perego, Carla, Baruscotti, Mirko, Bucchi, Annalisa, Del Giacco, Luca, Francolini, Maura
Cyhoeddwyd yn Sci Rep (2016)

Expression of skeletal but not cardiac Na(+) channel isoform preserves normal conduction in a depolarized cardiac syncytium

gan Protas, Lev, Dun, Wen, Jia, Zhiheng, Lu, Jia, Bucchi, Annalisa, Kumari, Sindhu, Chen, Ming, Cohen, Ira S., Rosen, Michael R., Entcheva, Emilia, Robinson, Richard B.
Cyhoeddwyd 2009

Deep bradycardia and heart block caused by inducible cardiac-specific knockout of the pacemaker channel gene Hcn4

gan Baruscotti, Mirko, Bucchi, Annalisa, Viscomi, Carlo, Mandelli, Giacomo, Consalez, Giacomo, Gnecchi-Rusconi, Tomaso, Montano, Nicola, Casali, Karina Rabello, Micheloni, Stefano, Barbuti, Andrea, DiFrancesco, Dario
Cyhoeddwyd 2011

Recessive Loss-of-Function Mutation in the Pacemaker HCN2 Channel Causing Increased Neuronal Excitability in a Patient with Idiopathic Generalized Epilepsy

gan DiFrancesco, Jacopo C., Barbuti, Andrea, Milanesi, Raffaella, Coco, Stefania, Bucchi, Annalisa, Bottelli, Georgia, Ferrarese, Carlo, Franceschetti, Silvana, Terragni, Benedetta, Baruscotti, Mirko, DiFrancesco, Dario
Cyhoeddwyd yn J Neurosci (2011)

A synthetic peptide that prevents cAMP regulation in mammalian hyperpolarization-activated cyclic nucleotide-gated (HCN) channels

gan Saponaro, Andrea, Cantini, Francesca, Porro, Alessandro, Bucchi, Annalisa, DiFrancesco, Dario, Maione, Vincenzo, Donadoni, Chiara, Introini, Bianca, Mesirca, Pietro, Mangoni, Matteo E, Thiel, Gerhard, Banci, Lucia, Santoro, Bina, Moroni, Anna
Cyhoeddwyd yn eLife (2018)

Exercise training reduces resting heart rate via downregulation of the funny channel HCN4

gan D’Souza, Alicia, Bucchi, Annalisa, Johnsen, Anne Berit, Logantha, Sunil Jit R.J., Monfredi, Oliver, Yanni, Joseph, Prehar, Sukhpal, Hart, George, Cartwright, Elizabeth, Wisloff, Ulrik, Dobryznski, Halina, DiFrancesco, Dario, Morris, Gwilym M., Boyett, Mark R.
Cyhoeddwyd 2014

The expression of the rare caveolin-3 variant T78M alters cardiac ion channels function and membrane excitability

gan Campostrini, Giulia, Bonzanni, Mattia, Lissoni, Alessio, Bazzini, Claudia, Milanesi, Raffaella, Vezzoli, Elena, Francolini, Maura, Baruscotti, Mirko, Bucchi, Annalisa, Rivolta, Ilaria, Fantini, Matteo, Severi, Stefano, Cappato, Riccardo, Crotti, Lia, J. Schwartz, Peter, DiFrancesco, Dario, Barbuti, Andrea
Cyhoeddwyd yn Cardiovasc Res (2017)

A Loss-of-Function HCN4 Mutation Associated With Familial Benign Myoclonic Epilepsy in Infancy Causes Increased Neuronal Excitability

gan Campostrini, Giulia, DiFrancesco, Jacopo C., Castellotti, Barbara, Milanesi, Raffaella, Gnecchi-Ruscone, Tomaso, Bonzanni, Mattia, Bucchi, Annalisa, Baruscotti, Mirko, Ferrarese, Carlo, Franceschetti, Silvana, Canafoglia, Laura, Ragona, Francesca, Freri, Elena, Labate, Angelo, Gambardella, Antonio, Costa, Cinzia, Gellera, Cinzia, Granata, Tiziana, Barbuti, Andrea, DiFrancesco, Dario
Cyhoeddwyd yn Front Mol Neurosci (2018)

A circadian clock in the sinus node mediates day-night rhythms in Hcn4 and heart rate

gan D’Souza, Alicia, Wang, Yanwen, Anderson, Cali, Bucchi, Annalisa, Baruscotti, Mirko, Olieslagers, Servé, Mesirca, Pietro, Johnsen, Anne Berit, Mastitskaya, Svetlana, Ni, Haibo, Zhang, Yu, Black, Nicholas, Cox, Charlotte, Wegner, Sven, Bano-Otalora, Beatriz, Petit, Cheryl, Gill, Eleanor, Logantha, Sunil Jit R.J., Dobrzynski, Halina, Ashton, Nick, Hart, George, Zhang, Rai, Zhang, Henggui, Cartwright, Elizabeth J., Wisloff, Ulrik, Mangoni, Matteo E., da Costa Martins, Paula A., Piggins, Hugh D., DiFrancesco, Dario, Boyett, Mark R.
Cyhoeddwyd yn Heart Rhythm (2021)

Mammalian γ2 AMPK regulates intrinsic heart rate

gan Yavari, Arash, Bellahcene, Mohamed, Bucchi, Annalisa, Sirenko, Syevda, Pinter, Katalin, Herring, Neil, Jung, Julia J., Tarasov, Kirill V., Sharpe, Emily J., Wolfien, Markus, Czibik, Gabor, Steeples, Violetta, Ghaffari, Sahar, Nguyen, Chinh, Stockenhuber, Alexander, Clair, Joshua R. St., Rimmbach, Christian, Okamoto, Yosuke, Yang, Dongmei, Wang, Mingyi, Ziman, Bruce D., Moen, Jack M., Riordon, Daniel R., Ramirez, Christopher, Paina, Manuel, Lee, Joonho, Zhang, Jing, Ahmet, Ismayil, Matt, Michael G., Tarasova, Yelena S., Baban, Dilair, Sahgal, Natasha, Lockstone, Helen, Puliyadi, Rathi, de Bono, Joseph, Siggs, Owen M., Gomes, John, Muskett, Hannah, Maguire, Mahon L., Beglov, Youlia, Kelly, Matthew, dos Santos, Pedro P. N., Bright, Nicola J., Woods, Angela, Gehmlich, Katja, Isackson, Henrik, Douglas, Gillian, Ferguson, David J. P., Schneider, Jürgen E., Tinker, Andrew, Wolkenhauer, Olaf, Channon, Keith M., Cornall, Richard J., Sternick, Eduardo B., Paterson, David J., Redwood, Charles S., Carling, David, Proenza, Catherine, David, Robert, Baruscotti, Mirko, DiFrancesco, Dario, Lakatta, Edward G., Watkins, Hugh, Ashrafian, Houman
Cyhoeddwyd yn Nat Commun (2017)