GATING OF HCN CHANNELS BY CYCLIC NUCLEOTIDES: RESIDUE CONTACTS THAT UNDERLIE LIGAND BINDING, SELECTIVITY AND EFFICACY

Por Zhou, Lei, Siegelbaum, Steven A.
Publicado em 2007

Effects of Surface Water on Protein Dynamics Studied by a Novel Coarse-Grained Normal Mode Approach

Por Zhou, Lei, Siegelbaum, Steven A.
Publicado em 2008

Pathway and Endpoint Free Energy Calculations for Cyclic Nucleotide Binding to HCN Channels

Por Zhou, Lei, Siegelbaum, Steven A.
Publicado em 2008

Recruitment of N-type Ca(2+) channels during LTP enhances low release efficacy of hippocampal CA1 perforant path synapses

Por Ahmed, Mohsin S., Siegelbaum, Steven A.
Publicado em 2009

Strong CA2 Pyramidal Neuron Synapses Define a Powerful Disynaptic Cortico-Hippocampal Loop

Por Chevaleyre, Vivien, Siegelbaum, Steven A.
Publicado em 2010

The Corticohippocampal Circuit, Synaptic Plasticity, and Memory

Por Basu, Jayeeta, Siegelbaum, Steven A.
Publicado no Cold Spring Harb Perspect Biol (2015)

The hippocampal CA2 region is essential for social memory

Por Hitti, Frederick L., Siegelbaum, Steven A.
Publicado em 2014

A novel role for synaptic inputs at distal dendrites: instructive signals for hippocampal long-term plasticity

Por Dudman, Joshua T., Tsay, David, Siegelbaum, Steven A.
Publicado em 2007

Properties of Hyperpolarization-Activated Pacemaker Current Defined by Coassembly of Hcn1 and Hcn2 Subunits and Basal Modulation by Cyclic Nucleotide

Por Chen, Shan, Wang, Jing, Siegelbaum, Steven A.
Publicado em 2001

Regulation of Hyperpolarization-Activated Hcn Channel Gating and Camp Modulation Due to Interactions of Cooh Terminus and Core Transmembrane Regions

Por Wang, Jing, Chen, Shan, Siegelbaum, Steven A.
Publicado em 2001

HCN1 Channels Constrain Synaptically Evoked Ca(2+) Spikes in Distal Dendrites of CA1 Pyramidal Neurons

Por Tsay, David, Dudman, Joshua T., Siegelbaum, Steven A.
Publicado em 2007

TRIP8b splice forms cooperate to regulate the localization and expression of HCN1 channels in CA1 pyramidal neurons

Por Piskorowski, Rebecca, Santoro, Bina, Siegelbaum, Steven A.
Publicado em 2011

C-Linker of Cyclic Nucleotide–gated Channels Controls Coupling of Ligand Binding to Channel Gating

Por Paoletti, Pierre, Young, Edgar C., Siegelbaum, Steven A.
Publicado em 1999

Hyperpolarization-activated cation channels inhibit EPSPs by interactions with M-type K(+) channels

Por George, Meena S., Abbott, L.F., Siegelbaum, Steven A.
Publicado em 2009

Synapses and Memory Storage

Por Mayford, Mark, Siegelbaum, Steven A., Kandel, Eric R.
Publicado em 2012

Efficient Coupling of Ligand Binding to Channel Opening by the Binding Domain of a Modulatory (β) Subunit of the Olfactory Cyclic Nucleotide-Gated Channel

Por Young, Edgar C., Sciubba, Daniel M., Siegelbaum, Steven A.
Publicado em 2001

Regulation of Gating and Rundown of HCN Hyperpolarization-activated Channels by Exogenous and Endogenous PIP(2)

Por Pian, Phillip, Bucchi, Annalisa, Robinson, Richard B., Siegelbaum, Steven A.
Publicado em 2006

Dendritic Na(+) spikes enable cortical input to drive action potential output from hippocampal CA2 pyramidal neurons

Por Sun, Qian, Srinivas, Kalyan V, Sotayo, Alaba, Siegelbaum, Steven A
Publicado no eLife (2014)

Voltage Sensor Movement and cAMP Binding Allosterically Regulate an Inherently Voltage-independent Closed−Open Transition in HCN Channels

Por Chen, Shan, Wang, Jing, Zhou, Lei, George, Meena S., Siegelbaum, Steven A.
Publicado em 2007

Transient expansion of synaptically connected dendritic spines upon induction of hippocampal long-term potentiation

Por Lang, Cynthia, Barco, Angel, Zablow, Leonard, Kandel, Eric R., Siegelbaum, Steven A., Zakharenko, Stanislav S.
Publicado em 2004