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HCN1 Channels Constrain Synaptically Evoked Ca(2+) Spikes in Distal Dendrites of CA1 Pyramidal Neurons

HCN1 hyperpolarization-activated cation channels act as an inhibitory constraint of both spatial learning and synaptic integration and long-term plasticity in the distal dendrites of hippocampal CA1 pyramidal neurons. However, as HCN1 channels provide an excitatory current, the mechanism of their in...

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Détails bibliographiques
Auteurs principaux: Tsay, David, Dudman, Joshua T., Siegelbaum, Steven A.
Format: Artigo
Langue:Inglês
Publié: 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2435011/
https://ncbi.nlm.nih.gov/pubmed/18093528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2007.11.015
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