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TRIP8b splice forms cooperate to regulate the localization and expression of HCN1 channels in CA1 pyramidal neurons

HCN1 channel subunits, which contribute to the hyperpolarization-activated cation current (Ih), are selectively targeted to distal apical dendrites of hippocampal CA1 pyramidal neurons. Here we addressed the importance of the brain-specific auxiliary subunit of HCN1, TRIP8b, in regulating HCN1 expre...

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Autori principali: Piskorowski, Rebecca, Santoro, Bina, Siegelbaum, Steven A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107038/
https://ncbi.nlm.nih.gov/pubmed/21555075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2011.03.023
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