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Binding of the auxiliary subunit TRIP8b to HCN channels shifts the mode of action of cAMP
Hyperpolarization-activated cyclic nucleotide–regulated cation (HCN) channels generate the hyperpolarization-activated cation current Ih present in many neurons. These channels are directly regulated by the binding of cAMP, which both shifts the voltage dependence of HCN channel opening to more posi...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The Rockefeller University Press
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3840918/ https://ncbi.nlm.nih.gov/pubmed/24277603 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201311013 |
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