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TRIP8b Regulates HCN1 Channel Trafficking and Gating through Two Distinct C-Terminal Interaction Sites

Hyperpolarization-activated cyclic nucleotide-regulated (HCN) channels in the brain associate with their auxiliary subunit TRIP8b (also known as PEX5R), a cytoplasmic protein expressed as a family of alternatively spliced isoforms. Recent in vitro and in vivo studies have shown that association of T...

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Detalhes bibliográficos
Main Authors: Santoro, Bina, Hu, Lei, Liu, Haiying, Saponaro, Andrea, Pian, Phillip, Piskorowski, Rebecca A., Moroni, Anna, Siegelbaum, Steven A.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077297/
https://ncbi.nlm.nih.gov/pubmed/21411649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5707-10.2011
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