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TRIP8b splice variants form a family of auxiliary subunits that regulate gating and trafficking of HCN channels in the brain

Hyperpolarization-activated cyclic nucleotide-regulated (HCN) channels, which generate the I(h) current, mediate a number of important brain functions. The HCN1 isoform regulates dendritic integration in cortical pyramidal neurons, and provides an inhibitory constraint on both working memory in pref...

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Detalhes bibliográficos
Main Authors: Santoro, Bina, Piskorowski, Rebecca A., Pian, Phillip, Hu, Lei, Liu, Haiying, Siegelbaum, Steven A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2720631/
https://ncbi.nlm.nih.gov/pubmed/19555649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2009.05.009
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