Rescuing cardiac automaticity in L‐type Cav1.3 channelopathies and beyond

Por Mesirca, Pietro, Bidaud, Isabelle, Mangoni, Matteo E.
Publicado no J Physiol (2016)

Functional role of voltage gated Ca(2+) channels in heart automaticity

Por Mesirca, Pietro, Torrente, Angelo G., Mangoni, Matteo E.
Publicado no Front Physiol (2015)

Control of heart rate by cAMP sensitivity of HCN channels

Por Alig, Jacqueline, Marger, Laurine, Mesirca, Pietro, Ehmke, Heimo, Mangoni, Matteo E., Isbrandt, Dirk
Publicado em 2009

Ion channel-kinase TRPM7 is required for maintaining cardiac automaticity

Por Sah, Rajan, Mesirca, Pietro, Van den Boogert, Marjolein, Rosen, Jonathan, Mably, John, Mangoni, Matteo E., Clapham, David E.
Publicado em 2013

Distinct localization and modulation of Ca(v)1.2 and Ca(v)1.3 L-type Ca(2+) channels in mouse sinoatrial node

Por Christel, Carl J, Cardona, Natalia, Mesirca, Pietro, Herrmann, Stefan, Hofmann, Franz, Striessnig, Joerg, Ludwig, Andreas, Mangoni, Matteo E, Lee, Amy
Publicado em 2012

The Timing of Myocardial Trpm7 Deletion during Cardiogenesis Variably Disrupts Adult Ventricular Function, Conduction and Repolarization

Por Sah, Rajan, Mesirca, Pietro, Mason, Xenos, Gibson, William, Bates-Withers, Christopher, Van den Boogert, Marjolein, Chaudhuri, Dipayan, Pu, William, Mangoni, Matteo E., Clapham, David E.
Publicado em 2013

Paradoxical Effect of Increased Diastolic Ca(2+) Release and Decreased Sinoatrial Node Activity in a Mouse Model of Catecholaminergic Polymorphic Ventricular Tachycardia

Por Neco, Patricia, Torrente, Angelo, Mesirca, Pietro, Zorio, Esther, Liu, Nian, Priori, Silvia G., Napolitano, Carlo, Richard, Sylvain, Benitah, Jean-Pierre, Mangoni, Matteo E., Gómez, Ana María
Publicado em 2012

Pacemaker activity and ionic currents in mouse atrioventricular node cells

Por Marger, Laurine, Mesirca, Pietro, Alig, Jacqueline, Torrente, Angelo, Dubel, Stefan, Engeland, Birgit, Kanani, Sandra, Fontanaud, Pierre, Striessnig, Jörg, Shin, Hee-Sup, Isbrandt, Dirk, Ehmke, Heimo, Nargeot, Joël, Mangoni, Matteo E
Publicado em 2011

Functional roles of Ca(v)1.3, Ca(v)3.1 and HCN channels in automaticity of mouse atrioventricular cells: Insights into the atrioventricular pacemaker mechanism

Por Marger, Laurine, Mesirca, Pietro, Alig, Jacqueline, Torrente, Angelo, Dubel, Stefan, Engeland, Birgit, Kanani, Sandra, Fontanaud, Pierre, Striessnig, Jörg, Shin, Hee-Sup, Isbrandt, Dirk, Ehmke, Heimo, Nargeot, Joël, Mangoni, Matteo E
Publicado em 2011

RyR(2)(R420Q) catecholaminergic polymorphic ventricular tachycardia mutation induces bradycardia by disturbing the coupled clock pacemaker mechanism

Por Wang, Yue Yi, Mesirca, Pietro, Marqués-Sulé, Elena, Zahradnikova, Alexandra, Villejoubert, Olivier, D’Ocon, Pilar, Ruiz, Cristina, Domingo, Diana, Zorio, Esther, Mangoni, Matteo E., Benitah, Jean-Pierre, Gómez, Ana María
Publicado no JCI Insight (2017)

G protein-gated I(KACh) channels as therapeutic targets for treatment of sick sinus syndrome and heart block

Por Mesirca, Pietro, Bidaud, Isabelle, Briec, François, Evain, Stéphane, Torrente, Angelo G., Le Quang, Khai, Leoni, Anne-Laure, Baudot, Matthias, Marger, Laurine, Chung You Chong, Antony, Nargeot, Joël, Striessnig, Joerg, Wickman, Kevin, Charpentier, Flavien, Mangoni, Matteo E.
Publicado no Proc Natl Acad Sci U S A (2016)

The G-protein–gated K(+) channel, I(KACh), is required for regulation of pacemaker activity and recovery of resting heart rate after sympathetic stimulation

Por Mesirca, Pietro, Marger, Laurine, Toyoda, Futoshi, Rizzetto, Riccardo, Audoubert, Matthieu, Dubel, Stefan, Torrente, Angelo G., DiFrancesco, Mattia L., Muller, Jana Christina, Leoni, Anne-Laure, Couette, Brigitte, Nargeot, Joël, Clapham, David E., Wickman, Kevin, Mangoni, Matteo E.
Publicado em 2013

Cardiac arrhythmia induced by genetic silencing of “funny” (f) channels is rescued by GIRK4 inactivation

Por Mesirca, Pietro, Alig, Jacqueline, Torrente, Angelo G., Müller, Jana Christina, Marger, Laurine, Rollin, Anne, Marquilly, Claire, Vincent, Anne, Dubel, Stefan, Bidaud, Isabelle, Fernandez, Anne, Seniuk, Anika, Engeland, Birgit, Singh, Jasmin, Miquerol, Lucile, Ehmke, Heimo, Eschenhagen, Thomas, Nargeot, Joel, Wickman, Kevin, Isbrandt, Dirk, Mangoni, Matteo E.
Publicado em 2014