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Ion channel-kinase TRPM7 is required for maintaining cardiac automaticity

Sick sinus syndrome and atrioventricular block are common clinical problems, often necessitating permanent pacemaker placement, yet the pathophysiology of these conditions remains poorly understood. Here we show that Transient Receptor Potential Melastatin 7 (TRPM7), a divalent-permeant channel-kina...

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Detalhes bibliográficos
Main Authors: Sah, Rajan, Mesirca, Pietro, Van den Boogert, Marjolein, Rosen, Jonathan, Mably, John, Mangoni, Matteo E., Clapham, David E.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740880/
https://ncbi.nlm.nih.gov/pubmed/23878236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1311865110
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