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Ion channel-kinase TRPM7 is required for maintaining cardiac automaticity

Sick sinus syndrome and atrioventricular block are common clinical problems, often necessitating permanent pacemaker placement, yet the pathophysiology of these conditions remains poorly understood. Here we show that Transient Receptor Potential Melastatin 7 (TRPM7), a divalent-permeant channel-kina...

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Bibliografische gegevens
Hoofdauteurs: Sah, Rajan, Mesirca, Pietro, Van den Boogert, Marjolein, Rosen, Jonathan, Mably, John, Mangoni, Matteo E., Clapham, David E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740880/
https://ncbi.nlm.nih.gov/pubmed/23878236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1311865110
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