A synthetic peptide that prevents cAMP regulation in mammalian hyperpolarization-activated cyclic nucleotide-gated (HCN) channels

Binding of TRIP8b to the cyclic nucleotide binding domain (CNBD) of mammalian hyperpolarization-activated cyclic nucleotide-gated (HCN) channels prevents their regulation by cAMP. Since TRIP8b is expressed exclusively in the brain, we envisage that it can be used for orthogonal control of HCN channe...

詳細記述

保存先:
書誌詳細
出版年:eLife
主要な著者: Saponaro, Andrea, Cantini, Francesca, Porro, Alessandro, Bucchi, Annalisa, DiFrancesco, Dario, Maione, Vincenzo, Donadoni, Chiara, Introini, Bianca, Mesirca, Pietro, Mangoni, Matteo E, Thiel, Gerhard, Banci, Lucia, Santoro, Bina, Moroni, Anna
フォーマット: Artigo
言語:Inglês
出版事項: eLife Sciences Publications, Ltd 2018
主題:
Structural Biology and Molecular Biophysics
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6023613/
https://ncbi.nlm.nih.gov/pubmed/29923826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.35753
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!

類似資料