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Mechanistic insights into arrhythmogenic right ventricular cardiomyopathy caused by desmocollin-2 mutations

AIMS: Recent immunohistochemical studies observed the loss of plakoglobin (PG) from the intercalated disc (ID) as a hallmark of arrhythmogenic right ventricular cardiomyopathy (ARVC), suggesting a final common pathway for this disease. However, the underlying molecular processes are poorly understoo...

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Detalhes bibliográficos
Main Authors: Gehmlich, Katja, Syrris, Petros, Peskett, Emma, Evans, Alison, Ehler, Elisabeth, Asimaki, Angeliki, Anastasakis, Aris, Tsatsopoulou, Adalena, Vouliotis, Apostolos-Ilias, Stefanadis, Christodoulos, Saffitz, Jeffrey E., Protonotarios, Nikos, McKenna, William J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3058729/
https://ncbi.nlm.nih.gov/pubmed/21062920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvq353
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