A novel desmocollin-2 mutation reveals insights into the molecular link between desmosomes and gap junctions

BACKGROUND: Cellular adhesion mediated by cardiac desmosomes is a prerequisite for proper electric propagation mediated by gap junctions in the myocardium. However, the molecular principles underlying this interdependence are not fully understood. OBJECTIVE: The purpose of this study was to determin...

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Detalhes bibliográficos
Main Authors: Gehmlich, Katja, Lambiase, Pier D., Asimaki, Angeliki, Ciaccio, Edward J., Ehler, Elisabeth, Syrris, Petros, Saffitz, Jeffrey E., McKenna, William J.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2011
Assuntos:
Clinical
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3085091/
https://ncbi.nlm.nih.gov/pubmed/21220045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.hrthm.2011.01.010
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