Aberrant developmental titin splicing and dysregulated sarcomere length in Thymosin β4 knockout mice

Sarcomere assembly is a highly orchestrated and dynamic process which adapts, during perinatal development, to accommodate growth of the heart. Sarcomeric components, including titin, undergo an isoform transition to adjust ventricular filling. Many sarcomeric genes have been implicated in congenita...

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Publicat a:J Mol Cell Cardiol
Autors principals: Smart, Nicola, Riegler, Johannes, Turtle, Cameron W., Lygate, Craig A., McAndrew, Debra J., Gehmlich, Katja, Dubé, Karina N., Price, Anthony N., Muthurangu, Vivek, Taylor, Andrew M., Lythgoe, Mark F., Redwood, Charles, Riley, Paul R.
Format: Artigo
Idioma:Inglês
Publicat: Academic Press 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5319848/
https://ncbi.nlm.nih.gov/pubmed/27914791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2016.10.010
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