Aberrant developmental titin splicing and dysregulated sarcomere length in Thymosin β4 knockout mice

Sarcomere assembly is a highly orchestrated and dynamic process which adapts, during perinatal development, to accommodate growth of the heart. Sarcomeric components, including titin, undergo an isoform transition to adjust ventricular filling. Many sarcomeric genes have been implicated in congenita...

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Detalhes bibliográficos
Publicado no:J Mol Cell Cardiol
Main Authors: Smart, Nicola, Riegler, Johannes, Turtle, Cameron W., Lygate, Craig A., McAndrew, Debra J., Gehmlich, Katja, Dubé, Karina N., Price, Anthony N., Muthurangu, Vivek, Taylor, Andrew M., Lythgoe, Mark F., Redwood, Charles, Riley, Paul R.
Formato: Artigo
Idioma:Inglês
Publicado em: Academic Press 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5319848/
https://ncbi.nlm.nih.gov/pubmed/27914791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2016.10.010
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