Thin filament length in the cardiac sarcomere varies with sarcomere length but is independent of titin and nebulin

Thin filament length (TFL) is an important determinant of the force-sarcomere length (SL) relation of cardiac muscle. However, the various mechanisms that control TFL are not well understood. Here we tested the previously proposed hypothesis that the actin-binding protein nebulin contributes to TFL...

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Detalhes bibliográficos
Publicado no:J Mol Cell Cardiol
Main Authors: Kolb, Justin, Li, Frank, Methawasin, Mei, Adler, Maya, Escobar, Yael-Natalie, Nedrud, Joshua, Pappas, Christopher T., Harris, Samantha P., Granzier, Henk
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584371/
https://ncbi.nlm.nih.gov/pubmed/27139341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2016.04.013
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