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The giant protein titin regulates the length of the striated muscle thick filament

The contractile machinery of heart and skeletal muscles has as an essential component the thick filament, comprised of the molecular motor myosin. The thick filament is of a precisely controlled length, defining thereby the force level that muscles generate and how this force varies with muscle leng...

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Podrobná bibliografie
Vydáno v:Nat Commun
Hlavní autoři: Tonino, Paola, Kiss, Balazs, Strom, Josh, Methawasin, Mei, Smith, John E., Kolb, Justin, Labeit, Siegfried, Granzier, Henk
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5648799/
https://ncbi.nlm.nih.gov/pubmed/29051486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01144-9
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