The giant protein titin regulates the length of the striated muscle thick filament

The contractile machinery of heart and skeletal muscles has as an essential component the thick filament, comprised of the molecular motor myosin. The thick filament is of a precisely controlled length, defining thereby the force level that muscles generate and how this force varies with muscle leng...

Full description

Saved in:
Bibliographic Details
Published in:Nat Commun
Main Authors: Tonino, Paola, Kiss, Balazs, Strom, Josh, Methawasin, Mei, Smith, John E., Kolb, Justin, Labeit, Siegfried, Granzier, Henk
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2017
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5648799/
https://ncbi.nlm.nih.gov/pubmed/29051486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01144-9
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items