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Cyclin B degradation leads to NuMA release from dynein/dynactin and from spindle poles

The protein NuMA localizes to mitotic spindle poles where it contributes to the organization of microtubules. In this study, we demonstrate that NuMA loses its stable association with the spindle poles after anaphase onset. Using extracts from Xenopus laevis eggs, we show that NuMA is dephosphorylat...

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Detalhes bibliográficos
Main Authors: Gehmlich, Katja, Haren, Laurence, Merdes, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1298957/
https://ncbi.nlm.nih.gov/pubmed/14710193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400046
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