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Cyclin B degradation leads to NuMA release from dynein/dynactin and from spindle poles

The protein NuMA localizes to mitotic spindle poles where it contributes to the organization of microtubules. In this study, we demonstrate that NuMA loses its stable association with the spindle poles after anaphase onset. Using extracts from Xenopus laevis eggs, we show that NuMA is dephosphorylat...

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Hlavní autoři: Gehmlich, Katja, Haren, Laurence, Merdes, Andreas
Médium: Artigo
Jazyk:Inglês
Vydáno: 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1298957/
https://ncbi.nlm.nih.gov/pubmed/14710193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400046
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