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Dynein–Dynactin–NuMA clusters generate cortical spindle-pulling forces as a multi-arm ensemble

To position the mitotic spindle within the cell, dynamic plus ends of astral microtubules are pulled by membrane-associated cortical force-generating machinery. However, in contrast to the chromosome-bound kinetochore structure, how the diffusion-prone cortical machinery is organized to generate lar...

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Bibliografski detalji
Izdano u:eLife
Glavni autori: Okumura, Masako, Natsume, Toyoaki, Kanemaki, Masato T, Kiyomitsu, Tomomi
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6037482/
https://ncbi.nlm.nih.gov/pubmed/29848445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.36559
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