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Formation of Spindle Poles by Dynein/Dynactin-Dependent Transport of Numa

NuMA is a large nuclear protein whose relocation to the spindle poles is required for bipolar mitotic spindle assembly. We show here that this process depends on directed NuMA transport toward microtubule minus ends powered by cytoplasmic dynein and its activator dynactin. Upon nuclear envelope brea...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Merdes, Andreas, Heald, Rebecca, Samejima, Kumiko, Earnshaw, William C., Cleveland, Don W.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Rockefeller University Press 2000
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2174573/
https://ncbi.nlm.nih.gov/pubmed/10811826
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