Rescue of Familial Cardiomyopathies by Modifications at the Level of Sarcomere and Ca(2+) Fluxes

Por Alves, Marco L., Gaffin, Robert D., Wolska, Beata M.
Publicado em 2010

Arginine–glycine–aspartic acid (RGD)-containing peptides inhibit the force production of mouse papillary muscle bundles via α(5)β(1) integrin

Por Sarin, Vandana, Gaffin, Robert D, Meininger, Gerald A, Muthuchamy, Mariappan
Publicado em 2005

Roles of phosphorylation of myosin binding protein-C and troponin I in mouse cardiac muscle twitch dynamics

Por Tong, Carl W, Gaffin, Robert D, Zawieja, David C, Muthuchamy, Mariappan
Publicado em 2004

Charged residue changes in the carboxy-terminus of α-tropomyosin alter mouse cardiac muscle contractility

Por Gaffin, Robert D, Gokulan, Kuppan, Sacchettini, James C, Hewett, Timothy, Klevitsky, Raisa, Robbins, Jeffrey, Muthuchamy, Mariappan
Publicado em 2004

Charged residue alterations in the inner-core domain and carboxy-terminus of α-tropomyosin differentially affect mouse cardiac muscle contractility

Por Gaffin, Robert D, Tong, Carl W, Zawieja, David C, Hewett, Timothy E, Klevitsky, Raisa, Robbins, Jeffrey, Muthuchamy, Mariappan
Publicado em 2004

Early sensitization of myofilaments to Ca(2+) prevents genetically linked dilated cardiomyopathy in mice

Por Alves, Marco L., Warren, Chad M., Simon, Jillian N., Gaffin, Robert D., Montminy, Eric M., Wieczorek, David F., Solaro, R. John, Wolska, Beata M.
Publicado no Cardiovasc Res (2017)

Effects of nicotine administration in a mouse model of familial hypertrophic cardiomyopathy, α-tropomyosin D175N

Por Gaffin, Robert D., Chowdhury, Shamim A. K., Alves, Marco S. L., Dias, Fernando A. L., Ribeiro, Cibele T. D., Fogaca, Rosalvo T. H., Wieczorek, David F., Wolska, Beata M.
Publicado em 2011

Long-term Rescue of a Familial Hypertrophic Cardiomyopathy Caused by a Mutation in the Thin Filament Protein, Tropomyosin, via Modulation of a Calcium Cycling Protein

Por Gaffin, Robert D, Peña, James R, Alves, Marco S L, Dias, Fernando A L, Chowdhury, Shamim, Heinrich, Lynley S, Goldspink, Paul H, Kranias, Evangelia G, Wieczorek, David F, Wolska, Beata M
Publicado em 2011

Neonatal Gene Transfer of Serca2a Delays Onset of Hypertrophic Remodeling and Improves Function in Familial Hypertrophic Cardiomyopathy

Por Peña, James R, Szkudlarek, Ariani C, Warren, Chad, Heinrich, Lynley S, Gaffin, Robert D., Jagatheesan, Ganapathy, del Monte, Federica, Hajjar, Roger J, Goldspink, Paul H, Solaro, R. John, Wieczorek, David F, Wolska, Beata M
Publicado em 2010

Desensitization of Myofilaments to Ca(2+) as a Therapeutic Target for Hypertrophic Cardiomyopathy with Mutations in Thin Filament Proteins

Por Alves, Marco L., Dias, Fernando A.L., Gaffin, Robert D., Simon, Jillian N., Montminy, Eric M., Biesiadecki, Brandon J., Hinken, Aaron C., Warren, Chad M., Utter, Megan S., Davis, Robert T., Sakthivel, Sadayappan, Robbins, Jeffrey, Wieczorek, David F., Solaro, R. John, Wolska, Beata M.
Publicado em 2014