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Charged residue changes in the carboxy-terminus of α-tropomyosin alter mouse cardiac muscle contractility
Striated muscle tropomyosin (TM) is an essential thin filament protein that is sterically and allosterically involved in calcium-mediated cardiac contraction. We have previously shown that overexpressing the β-TM isoform in mouse hearts leads to physiological changes in myocardial relaxation and Ca(...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Blackwell Science Inc
2004
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1664955/ https://ncbi.nlm.nih.gov/pubmed/14766940 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2003.058487 |
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