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Arginine–glycine–aspartic acid (RGD)-containing peptides inhibit the force production of mouse papillary muscle bundles via α(5)β(1) integrin

Integrins are considered to be an important mechanosensor in cardiac myocytes. To test whether integrins can influence cardiac contractile function, the force–frequency relationships of mouse papillary muscle bundles were measured in the presence or absence of a synthetic integrin-binding peptide, G...

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Autors principals: Sarin, Vandana, Gaffin, Robert D, Meininger, Gerald A, Muthuchamy, Mariappan
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1464440/
https://ncbi.nlm.nih.gov/pubmed/15718258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2005.083238
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