Decreasing Tropomyosin Phosphorylation Rescues Tropomyosin-induced Familial Hypertrophic Cardiomyopathy

Studies indicate that tropomyosin (Tm) phosphorylation status varies in different mouse models of cardiac disease. Investigation of basal and acute cardiac function utilizing a mouse model expressing an α-Tm protein that cannot be phosphorylated (S283A) shows a compensated hypertrophic phenotype wit...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Schulz, Emily M., Wilder, Tanganyika, Chowdhury, Shamim A. K., Sheikh, Hajer N., Wolska, Beata M., Solaro, R. John, Wieczorek, David F.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2013
Gaiak:
Cell Biology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3789987/
https://ncbi.nlm.nih.gov/pubmed/23960072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.466466
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