Decreasing Tropomyosin Phosphorylation Rescues Tropomyosin-induced Familial Hypertrophic Cardiomyopathy

Studies indicate that tropomyosin (Tm) phosphorylation status varies in different mouse models of cardiac disease. Investigation of basal and acute cardiac function utilizing a mouse model expressing an α-Tm protein that cannot be phosphorylated (S283A) shows a compensated hypertrophic phenotype wit...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Schulz, Emily M., Wilder, Tanganyika, Chowdhury, Shamim A. K., Sheikh, Hajer N., Wolska, Beata M., Solaro, R. John, Wieczorek, David F.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2013
Témata:
Cell Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3789987/
https://ncbi.nlm.nih.gov/pubmed/23960072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.466466
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky