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Decreasing Tropomyosin Phosphorylation Rescues Tropomyosin-induced Familial Hypertrophic Cardiomyopathy

Studies indicate that tropomyosin (Tm) phosphorylation status varies in different mouse models of cardiac disease. Investigation of basal and acute cardiac function utilizing a mouse model expressing an α-Tm protein that cannot be phosphorylated (S283A) shows a compensated hypertrophic phenotype wit...

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書誌詳細
主要な著者: Schulz, Emily M., Wilder, Tanganyika, Chowdhury, Shamim A. K., Sheikh, Hajer N., Wolska, Beata M., Solaro, R. John, Wieczorek, David F.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3789987/
https://ncbi.nlm.nih.gov/pubmed/23960072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.466466
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