Analyses of more than 60,000 exomes questions the role of numerous genes previously associated with dilated cardiomyopathy

Por Nouhravesh, Nina, Ahlberg, Gustav, Ghouse, Jonas, Andreasen, Charlotte, Svendsen, Jesper H., Haunsø, Stig, Bundgaard, Henning, Weeke, Peter E., Olesen, Morten S.
Publicado no Mol Genet Genomic Med (2016)

Integrating EMR-Linked and In Vivo Functional Genetic Data to Identify New Genotype-Phenotype Associations

Por Mosley, Jonathan D., Van Driest, Sara L., Weeke, Peter E., Delaney, Jessica T., Wells, Quinn S., Bastarache, Lisa, Roden, Dan M., Denny, Josh C.
Publicado em 2014

Using Systems Approaches to Address Challenges for Clinical Implementation of Pharmacogenomics

Por Karnes, Jason H, Van Driest, Sara, Bowton, Erica A, Weeke, Peter E, Mosley, Jonathan D, Peterson, Josh F, Denny, Joshua C, Roden, Dan M
Publicado em 2013

Population‐specific single‐nucleotide polymorphism confers increased risk of venous thromboembolism in African Americans

Por Daneshjou, Roxana, Cavallari, Larisa H., Weeke, Peter E., Karczewski, Konrad J., Drozda, Katarzyna, Perera, Minoli A., Johnson, Julie A., Klein, Teri E., Bustamante, Carlos D., Roden, Dan M., Shaffer, Christian, Denny, Joshua C., Zehnder, James L., Altman, Russ B.
Publicado no Mol Genet Genomic Med (2016)

A genome-wide association study of heparin-induced thrombocytopenia using an electronic medical record

Por Karnes, Jason H, Cronin, Robert M, Rollin, Jerome, Teumer, Alexander, Pouplard, Claire, Shaffer, Christian M, Blanquicett, Carmelo, Bowton, Erica A, Cowan, James D, Mosley, Jonathan D, Van Driest, Sara L, Weeke, Peter E, Wells, Quinn S, Bakchoul, Tamam, Denny, Joshua C, Greinacher, Andreas, Gruel, Yves, Roden, Dan M
Publicado no Thromb Haemost (2014)

Mechanistic Phenotypes: An Aggregative Phenotyping Strategy to Identify Disease Mechanisms Using GWAS Data

Por Mosley, Jonathan D., Van Driest, Sara L., Larkin, Emma K., Weeke, Peter E., Witte, John S., Wells, Quinn S., Karnes, Jason H., Guo, Yan, Bastarache, Lisa, Olson, Lana M., McCarty, Catherine A., Pacheco, Jennifer A., Jarvik, Gail P., Carrell, David S., Larson, Eric B., Crosslin, David R., Kullo, Iftikhar J., Tromp, Gerard, Kuivaniemi, Helena, Carey, David J., Ritchie, Marylyn D., Denny, Josh C., Roden, Dan M.
Publicado em 2013

Genome-wide association and pathway analysis of left ventricular function after anthracycline exposure in adults

Por Wells, Quinn S., Veatch, Olivia J., Fessel, Joshua P., Joon, Aron Y., Levinson, Rebecca T., Mosley, Jonathan D., Held, Elizabeth P., Lindsay, Chase S., Shaffer, Christian M., Weeke, Peter E., Glazer, Andrew M., Bersell, Kevin R., Van Driest, Sara L., Karnes, Jason H., Blair, Marcia A., Lagrone, Lore W., Su, Yan R., Bowton, Erica A., Feng, Ziding, Ky, Bonnie, Lenihan, Daniel J., Fisch, Michael J., Denny, Joshua C., Roden, Dan M.
Publicado no Pharmacogenet Genomics (2017)

Four Susceptibility Loci for Gallstone Disease Identified in a Meta-analysis of Genome-wide Association Studies

Por Joshi, Amit D., Andersson, Charlotte, Buch, Stephan, Stender, Stefan, Noordam, Raymond, Weng, Lu-Chen, Weeke, Peter E., Auer, Paul L., Boehm, Bernhard, Chen, Constance, Choi, Hyon, Curhan, Gary, Denny, Joshua C., De Vivo, Immaculata, Eicher, John D., Ellinghaus, David, Folsom, Aaron R., Fuchs, Charles, Gala, Manish, Haessler, Jeffrey, Hofman, Albert, Hu, Frank, Hunter, David J., Janssen, Harry L.A., Kang, Jae H., Kooperberg, Charles, Kraft, Peter, Kratzer, Wolfgang, Lieb, Wolfgang, Lutsey, Pamela L., Murad, Sarwa Darwish, Nordestgaard, Børge G., Pasquale, Louis R., Reiner, Alex P., Ridker, Paul M, Rimm, Eric, Rose, Lynda M., Shaffer, Christian M., Schafmayer, Clemens, Tamimi, Rulla M., Uitterlinden, André G, Völker, Uwe, Völzke, Henry, Wakabayashi, Yoshiyuki, Wiggs, Janey L., Zhu, Jun, Roden, Dan M., Stricker, Bruno H., Tang, Weihong, Teumer, Alexander, Hampe, Jochen, Tybjærg-Hansen, Anne, Chasman, Daniel I., Chan, Andrew T., Johnson, Andrew D.
Publicado no Gastroenterology (2016)

Genetic Interactions with Age, Sex, Body Mass Index, and Hypertension in Relation to Atrial Fibrillation: The AFGen Consortium

Por Weng, Lu-Chen, Lunetta, Kathryn L., Müller-Nurasyid, Martina, Smith, Albert Vernon, Thériault, Sébastien, Weeke, Peter E., Barnard, John, Bis, Joshua C., Lyytikäinen, Leo-Pekka, Kleber, Marcus E., Martinsson, Andreas, Lin, Henry J., Rienstra, Michiel, Trompet, Stella, Krijthe, Bouwe P., Dörr, Marcus, Klarin, Derek, Chasman, Daniel I., Sinner, Moritz F., Waldenberger, Melanie, Launer, Lenore J., Harris, Tamara B., Soliman, Elsayed Z., Alonso, Alvaro, Paré, Guillaume, Teixeira, Pedro L., Denny, Joshua C., Shoemaker, M. Benjamin, Van Wagoner, David R., Smith, Jonathan D., Psaty, Bruce M., Sotoodehnia, Nona, Taylor, Kent D., Kähönen, Mika, Nikus, Kjell, Delgado, Graciela E., Melander, Olle, Engström, Gunnar, Yao, Jie, Guo, Xiuqing, Christophersen, Ingrid E., Ellinor, Patrick T., Geelhoed, Bastiaan, Verweij, Niek, Macfarlane, Peter, Ford, Ian, Heeringa, Jan, Franco, Oscar H., Uitterlinden, André G., Völker, Uwe, Teumer, Alexander, Rose, Lynda M., Kääb, Stefan, Gudnason, Vilmundur, Arking, Dan E., Conen, David, Roden, Dan M., Chung, Mina K., Heckbert, Susan R., Benjamin, Emelia J., Lehtimäki, Terho, März, Winfried, Smith, J. Gustav, Rotter, Jerome I., van der Harst, Pim, Jukema, J. Wouter, Stricker, Bruno H., Felix, Stephan B., Albert, Christine M., Lubitz, Steven A.
Publicado no Sci Rep (2017)

Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease

Por Webb, Thomas R., Erdmann, Jeanette, Stirrups, Kathleen E., Stitziel, Nathan O., Masca, Nicholas G.D., Jansen, Henning, Kanoni, Stavroula, Nelson, Christopher P., Ferrario, Paola G., König, Inke R., Eicher, John D., Johnson, Andrew D., Hamby, Stephen E., Betsholtz, Christer, Ruusalepp, Arno, Franzén, Oscar, Schadt, Eric E., Björkegren, Johan L.M., Weeke, Peter E., Auer, Paul L., Schick, Ursula M., Lu, Yingchang, Zhang, He, Dube, Marie-Pierre, Goel, Anuj, Farrall, Martin, Peloso, Gina M., Won, Hong-Hee, Do, Ron, van Iperen, Erik, Kruppa, Jochen, Mahajan, Anubha, Scott, Robert A., Willenborg, Christina, Braund, Peter S., van Capelleveen, Julian C., Doney, Alex S.F., Donnelly, Louise A., Asselta, Rosanna, Merlini, Pier A., Duga, Stefano, Marziliano, Nicola, Denny, Josh C., Shaffer, Christian, El-Mokhtari, Nour Eddine, Franke, Andre, Heilmann, Stefanie, Hengstenberg, Christian, Hoffmann, Per, Holmen, Oddgeir L., Hveem, Kristian, Jansson, Jan-Håkan, Jöckel, Karl-Heinz, Kessler, Thorsten, Kriebel, Jennifer, Laugwitz, Karl L., Marouli, Eirini, Martinelli, Nicola, McCarthy, Mark I., Van Zuydam, Natalie R., Meisinger, Christa, Esko, Tõnu, Mihailov, Evelin, Escher, Stefan A., Alver, Maris, Moebus, Susanne, Morris, Andrew D., Virtamo, Jarma, Nikpay, Majid, Olivieri, Oliviero, Provost, Sylvie, AlQarawi, Alaa, Robertson, Neil R., Akinsansya, Karen O., Reilly, Dermot F., Vogt, Thomas F., Yin, Wu, Asselbergs, Folkert W., Kooperberg, Charles, Jackson, Rebecca D., Stahl, Eli, Müller-Nurasyid, Martina, Strauch, Konstantin, Varga, Tibor V., Waldenberger, Melanie, Zeng, Lingyao, Chowdhury, Rajiv, Salomaa, Veikko, Ford, Ian, Jukema, J. Wouter, Amouyel, Philippe, Kontto, Jukka, Nordestgaard, Børge G., Ferrières, Jean, Saleheen, Danish, Sattar, Naveed, Surendran, Praveen, Wagner, Aline, Young, Robin, Howson, Joanna M.M., Butterworth, Adam S., Danesh, John, Ardissino, Diego, Bottinger, Erwin P., Erbel, Raimund, Franks, Paul W., Girelli, Domenico, Hall, Alistair S., Hovingh, G. Kees, Kastrati, Adnan, Lieb, Wolfgang, Meitinger, Thomas, Kraus, William E., Shah, Svati H., McPherson, Ruth, Orho-Melander, Marju, Melander, Olle, Metspalu, Andres, Palmer, Colin N.A., Peters, Annette, Rader, Daniel J., Reilly, Muredach P., Loos, Ruth J.F., Reiner, Alex P., Roden, Dan M., Tardif, Jean-Claude, Thompson, John R., Wareham, Nicholas J., Watkins, Hugh, Willer, Cristen J., Samani, Nilesh J., Schunkert, Heribert, Deloukas, Panos, Kathiresan, Sekar
Publicado no J Am Coll Cardiol (2017)

Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation

Por Christophersen, Ingrid E., Rienstra, Michiel, Roselli, Carolina, Yin, Xiaoyan, Geelhoed, Bastiaan, Barnard, John, Lin, Honghuang, Arking, Dan E., Smith, Albert V., Albert, Christine M., Chaffin, Mark, Tucker, Nathan R., Li, Molong, Klarin, Derek, Bihlmeyer, Nathan A, Low, Siew-Kee, Weeke, Peter E., Müller-Nurasyid, Martina, Smith, J. Gustav, Brody, Jennifer A., Niemeijer, Maartje N., Dörr, Marcus, Trompet, Stella, Huffman, Jennifer, Gustafsson, Stefan, Schurman, Claudia, Kleber, Marcus E., Lyytikäinen, Leo-Pekka, Seppälä, Ilkka, Malik, Rainer, Horimoto, Andrea R. V. R., Perez, Marco, Sinisalo, Juha, Aeschbacher, Stefanie, Thériault, Sébastien, Yao, Jie, Radmanesh, Farid, Weiss, Stefan, Teumer, Alexander, Choi, Seung Hoan, Weng, Lu-Chen, Clauss, Sebastian, Deo, Rajat, Rader, Daniel J., Shah, Svati, Sun, Albert, Hopewell, Jemma C., Debette, Stephanie, Chauhan, Ganesh, Yang, Qiong, Worrall, Bradford B., Paré, Guillaume, Kamatani, Yoichiro, Hagemeijer, Yanick P., Verweij, Niek, Siland, Joylene E., Kubo, Michiaki, Smith, Jonathan D., Van Wagoner, David R., Bis, Joshua C., Perz, Siegfried, Psaty, Bruce M., Ridker, Paul M., Magnani, Jared W., Harris, Tamara B., Launer, Lenore J., Shoemaker, M. Benjamin, Padmanabhan, Sandosh, Haessler, Jeffrey, Bartz, Traci M., Waldenberger, Melanie, Lichtner, Peter, Arendt, Marina, Krieger, Jose E., Kähönen, Mika, Risch, Lorenz, Mansur, Alfredo J., Peters, Annette, Smith, Blair H., Lind, Lars, Scott, Stuart A., Lu, Yingchang, Bottinger, Erwin B., Hernesniemi, Jussi, Lindgren, Cecilia M., Wong, Jorge, Huang, Jie, Eskola, Markku, Morris, Andrew P., Ford, Ian, Reiner, Alex P., Delgado, Graciela, Chen, Lin Y., Chen, Yii-Der Ida, Sandhu, Roopinder K., Li, Man, Boerwinkle, Eric, Eisele, Lewin, Lannfelt, Lars, Rost, Natalia, Anderson, Christopher D., Taylor, Kent D., Campbell, Archie, Magnusson, Patrik K., Porteous, David, Hocking, Lynne J., Vlachopoulou, Efthymia, Pedersen, Nancy L., Nikus, Kjell, Orho-Melander, Marju, Hamsten, Anders, Heeringa, Jan, Denny, Joshua C., Kriebel, Jennifer, Darbar, Dawood, Newton-Cheh, Christopher, Shaffer, Christian, Macfarlane, Peter W., Heilmann, Stefanie, Almgren, Peter, Huang, Paul L., Sotoodehnia, Nona, Soliman, Elsayed Z., Uitterlinden, Andre G., Hofman, Albert, Franco, Oscar H., Völker, Uwe, Jöckel, Karl-Heinz, Sinner, Moritz F., Lin, Henry J., Guo, Xiuqing, Dichgans, Martin, Ingelsson, Erik, Kooperberg, Charles, Melander, Olle, Loos, Ruth J. F., Laurikka, Jari, Conen, David, Rosand, Jonathan, van der Harst, Pim, Lokki, Marja-Liisa, Kathiresan, Sekar, Pereira, Alexandre, Jukema, J. Wouter, Hayward, Caroline, Rotter, Jerome I., März, Winfried, Lehtimäki, Terho, Stricker, Bruno H., Chung, Mina K., Felix, Stephan B., Gudnason, Vilmundur, Alonso, Alvaro, Roden, Dan M., Kääb, Stefan, Chasman, Daniel I., Heckbert, Susan R., Benjamin, Emelia J., Tanaka, Toshihiro, Lunetta, Kathryn L., Lubitz, Steven A., Ellinor, Patrick T.
Publicado no Nat Genet (2017)

Exome-wide association study of plasma lipids in >300,000 individuals

Por Liu, Dajiang J., Peloso, Gina M., Yu, Haojie, Butterworth, Adam S., Wang, Xiao, Mahajan, Anubha, Saleheen, Danish, Emdin, Connor, Alam, Dewan, Alves, Alexessander Couto, Amouyel, Philippe, di Angelantonio, Emanuele, Arveiler, Dominique, Assimes, Themistocles L., Auer, Paul L., Baber, Usman, Ballantyne, Christie M., Bang, Lia E., Benn, Marianne, Bis, Joshua C., Boehnke, Michael, Boerwinkle, Eric, Bork-Jensen, Jette, Bottinger, Erwin P., Brandslund, Ivan, Brown, Morris, Busonero, Fabio, Caulfield, Mark J, Chambers, John C, Chasman, Daniel I., Chen, Y. Eugene, Chen, Yii-Der Ida, Chowdhury, Rajiv, Christensen, Cramer, Chu, Audrey Y., Connell, John M, Cucca, Francesco, Cupples, L. Adrienne, Damrauer, Scott M., Davies, Gail, Deary, Ian J, Dedoussis, George, Denny, Joshua C., Dominiczak, Anna, Dubé, Marie-Pierre, Ebeling, Tapani, Eiriksdottir, Gudny, Esko, Tõnu, Farmaki, Aliki-Eleni, Feitosa, Mary F, Ferrario, Marco, Ferrieres, Jean, Ford, Ian, Fornage, Myriam, Franks, Paul W., Frayling, Timothy M., Frikke-Schmidt, Ruth, Fritsche, Lars, Frossard, Philippe, Fuster, Valentin, Ganesh, Santhi K., Gao, Wei, Garcia, Melissa E., Gieger, Christian, Giulianini, Franco, Goodarzi, Mark O., Grallert, Harald, Grarup, Niels, Groop, Leif, Grove, Megan L., Gudnason, Vilmundur, Hansen, Torben, Harris, Tamara B., Hayward, Caroline, Hirschhorn, Joel N., Holmen, Oddgeir L., Huffman, Jennifer, Huo, Yong, Hveem, Kristian, Jabeen, Sehrish, Jackson, Anne U, Jakobsdottir, Johanna, Jarvelin, Marjo-Riitta, Jensen, Gorm B, Jørgensen, Marit E., Jukema, J. Wouter, Justesen, Johanne M., Kamstrup, Pia R., Kanoni, Stavroula, Karpe, Fredrik, Kee, Frank, Khera, Amit V., Klarin, Derek, Koistinen, Heikki A., Kooner, Jaspal S, Kooperberg, Charles, Kuulasmaa, Kari, Kuusisto, Johanna, Laakso, Markku, Lakka, Timo, Langenberg, Claudia, Langsted, Anne, Launer, Lenore J., Lauritzen, Torsten, Liewald, David CM, Lin, Li An, Linneberg, Allan, Loos, Ruth J.F., Lu, Yingchang, Lu, Xiangfeng, Mägi, Reedik, Malarstig, Anders, Manichaikul, Ani, Manning, Alisa K., Mäntyselkä, Pekka, Marouli, Eirini, Masca, Nicholas GD, Maschio, Andrea, Meigs, James B., Melander, Olle, Metspalu, Andres, Morris, Andrew P, Morrison, Alanna C., Mulas, Antonella, Müller-Nurasyid, Martina, Munroe, Patricia B., Neville, Matt J, Nielsen, Jonas B., Nielsen, Sune F, Nordestgaard, Børge G, Ordovas, Jose M., Mehran, Roxana, O’Donnell, Christoper J., Orho-Melander, Marju, Molony, Cliona M., Muntendam, Pieter, Padmanabhan, Sandosh, Palmer, Colin NA, Pasko, Dorota, Patel, Aniruddh P., Pedersen, Oluf, Perola, Markus, Peters, Annette, Pisinger, Charlotta, Pistis, Giorgio, Polasek, Ozren, Poulter, Neil, Psaty, Bruce M., Rader, Daniel J., Rasheed, Asif, Rauramaa, Rainer, Reilly, Dermot, Reiner, Alex P., Renström, Frida, Rich, Stephen S, Ridker, Paul M, Rioux, John D., Robertson, Neil R, Roden, Dan M., Rotter, Jerome I., Rudan, Igor, Salomaa, Veikko, Samani, Nilesh J, Sanna, Serena, Sattar, Naveed, Schmidt, Ellen M., Scott, Robert A., Sever, Peter, Sevilla, Raquel S., Shaffer, Christian M., Sim, Xueling, Sivapalaratnam, Suthesh, Small, Kerrin S, Smith, Albert V., Smith, Blair H, Somayajula, Sangeetha, Southam, Lorraine, Spector, Timothy D, Speliotes, Elizabeth K., Starr, John M, Stirrups, Kathleen E, Stitziel, Nathan, Strauch, Konstantin, Stringham, Heather M, Surendran, Praveen, Tada, Hayato, Tall, Alan R., Tang, Hua, Tardif, Jean-Claude, Taylor, Kent D, Trompet, Stella, Tsao, Philip S., Tuomilehto, Jaakko, Tybjaerg-Hansen, Anne, van Zuydam, Natalie R, Varbo, Anette, Varga, Tibor V, Virtamo, Jarmo, Waldenberger, Melanie, Wang, Nan, Wareham, Nick J., Warren, Helen R, Weeke, Peter E., Weinstock, Joshua, Wessel, Jennifer, Wilson, James G., Wilson, Peter W. F., Xu, Ming, Yaghootkar, Hanieh, Young, Robin, Zeggini, Eleftheria, Zhang, He, Zheng, Neil S., Zhang, Weihua, Zhang, Yan, Zhou, Wei, Zhou, Yanhua, Zoledziewska, Magdalena, Howson, Joanna MM, Danesh, John, McCarthy, Mark I, Cowan, Chad, Abecasis, Goncalo, Deloukas, Panos, Musunuru, Kiran, Willer, Cristen J., Kathiresan, Sekar
Publicado no Nat Genet (2017)