Gene Expression Profiles for the Identification of Prevalent Atrial Fibrillation

por Thériault, Sébastien, Whitlock, Richard, Raman, Kripa, Vincent, Jessica, Yusuf, Salim, Paré, Guillaume
Publicado no J Am Heart Assoc (2017)

Phenome-wide analyses establish a specific association between aortic valve PALMD expression and calcific aortic valve stenosis

por Li, Zhonglin, Gaudreault, Nathalie, Arsenault, Benoit J., Mathieu, Patrick, Bossé, Yohan, Thériault, Sébastien
Publicado no Commun Biol (2020)

A Mendelian randomization study of IL6 signaling in cardiovascular diseases, immune-related disorders and longevity

por Rosa, Mickael, Chignon, Arnaud, Li, Zhonglin, Boulanger, Marie-Chloé, Arsenault, Benoit J., Bossé, Yohan, Thériault, Sébastien, Mathieu, Patrick
Publicado no NPJ Genom Med (2019)

Single-cell expression and Mendelian randomization analyses identify blood genes associated with lifespan and chronic diseases

por Chignon, Arnaud, Bon-Baret, Valentin, Boulanger, Marie-Chloé, Li, Zhonglin, Argaud, Deborah, Bossé, Yohan, Thériault, Sébastien, Arsenault, Benoit J., Mathieu, Patrick
Publicado no Commun Biol (2020)

System Genetics Including Causal Inference Identify Immune Targets for Coronary Artery Disease and the Lifespan

por Bon-Baret, Valentin, Chignon, Arnaud, Boulanger, Marie-Chloé, Li, Zhonglin, Argaud, Deborah, Arsenault, Benoit J., Thériault, Sébastien, Bossé, Yohan, Mathieu, Patrick
Publicado no Circ Genom Precis Med (2021)

A transcriptome-wide association study identifies PALMD as a susceptibility gene for calcific aortic valve stenosis

por Thériault, Sébastien, Gaudreault, Nathalie, Lamontagne, Maxime, Rosa, Mickael, Boulanger, Marie-Chloé, Messika-Zeitoun, David, Clavel, Marie-Annick, Capoulade, Romain, Dagenais, François, Pibarot, Philippe, Mathieu, Patrick, Bossé, Yohan
Publicado no Nat Commun (2018)

Association of Long-term Exposure to Elevated Lipoprotein(a) Levels With Parental Life Span, Chronic Disease–Free Survival, and Mortality Risk: A Mendelian Randomization Analysis

por Arsenault, Benoit J., Pelletier, William, Kaiser, Yannick, Perrot, Nicolas, Couture, Christian, Khaw, Kay-Tee, Wareham, Nicholas J., Bossé, Yohan, Pibarot, Philippe, Stroes, Erik S. G., Mathieu, Patrick, Thériault, Sébastien, Boekholdt, S. Matthijs
Publicado no JAMA Netw Open (2020)

Enhancer-associated aortic valve stenosis risk locus 1p21.2 alters NFATC2 binding site and promotes fibrogenesis

por Chignon, Arnaud, Rosa, Mickael, Boulanger, Marie-Chloé, Argaud, Déborah, Devillers, Romain, Bon-Baret, Valentin, Mkannez, Ghada, Li, Zhonglin, Rufiange, Anne, Gaudreault, Nathalie, Gosselin, David, Thériault, Sébastien, Bossé, Yohan, Mathieu, Patrick
Publicado no iScience (2021)

Electronic Health Record-Based Genome-Wide Meta-Analysis Identifies New Susceptibility Loci for Non-Alcoholic Fatty Liver Disease

por Ghodsian, Nooshin, Abner, Erik, Gobeil, Émilie, Taba, Nele, Amand, Alexis St-, Perrot, Nicolas, Couture, Christian, Bossé, Yohan, Mitchell, Patricia, Vohl, Marie-Claude, Thériault, Sébastien, Tchernof, André, Esko, Tõnu, Mathieu, Patrick, Arsenault, Benoit
Publicado no J Endocr Soc (2021)

Genome-Wide Meta-Analysis and Mendelian Randomization Identify Early Biomarkers of Non-Alcoholic Fatty Liver Disease

por Gobeil, Emilie, Abner, Erik, Ghodsian, Nooshin, Taba, Nele, St-Amand, Alexis, Perrot, Nicolas, Couture, Christian, Mitchell, Patricia, Bossé, Yohan, Mathieu, Patrick, Vohl, Marie-Claude, Thériault, Sébastien, Tchernof, Andre, Esko, Tõnu, Arsenault, Benoit J
Publicado no J Endocr Soc (2021)

Lipoprotein Proteomics and Aortic Valve Transcriptomics Identify Biological Pathways Linking Lipoprotein(a) Levels to Aortic Stenosis

por Bourgeois, Raphaëlle, Bourgault, Jérôme, Despres, Audrey-Anne, Perrot, Nicolas, Guertin, Jakie, Girard, Arnaud, Mitchell, Patricia L., Gotti, Clarisse, Bourassa, Sylvie, Scipione, Corey A., Gaudreault, Nathalie, Boffa, Michael B., Koschinsky, Marlys L., Pibarot, Philippe, Droit, Arnaud, Thériault, Sébastien, Mathieu, Patrick, Bossé, Yohan, Arsenault, Benoit J.
Publicado no Metabolites (2021)

A Comparative Analysis of the Lipoprotein(a) and Low-Density Lipoprotein Proteomic Profiles Combining Mass Spectrometry and Mendelian Randomization

por Bourgeois, Raphaëlle, Girard, Arnaud, Perrot, Nicolas, Guertin, Jakie, Mitchell, Patricia L., Couture, Christian, Gotti, Clarisse, Bourassa, Sylvie, Poggio, Paolo, Mass, Elvira, Capoulade, Romain, Scipione, Corey A., Després, Audrey-Anne, Couture, Patrick, Droit, Arnaud, Pibarot, Philippe, Boffa, Michael B., Thériault, Sébastien, Koschinsky, Marlys L., Mathieu, Patrick, Arsenault, Benoit J.
Publicado no CJC Open (2020)

Lipoprotein(a), Oxidized Phospholipids, and Aortic Valve Microcalcification Assessed by 18F-Sodium Fluoride Positron Emission Tomography and Computed Tomography

por Després, Audrey-Anne, Perrot, Nicolas, Poulin, Anthony, Tastet, Lionel, Shen, Mylène, Chen, Hao Yu, Bourgeois, Raphaëlle, Trottier, Mikaël, Tessier, Michel, Guimond, Jean, Nadeau, Maxime, Engert, James C., Thériault, Sébastien, Bossé, Yohan, Witztum, Joseph L., Couture, Patrick, Mathieu, Patrick, Dweck, Marc R., Tsimikas, Sotirios, Thanassoulis, George, Pibarot, Philippe, Clavel, Marie-Annick, Arsenault, Benoit J.
Publicado no CJC Open (2019)

Prioritization of candidate causal genes for asthma in susceptibility loci derived from UK Biobank

por Valette, Kim, Li, Zhonglin, Bon-Baret, Valentin, Chignon, Arnaud, Bérubé, Jean-Christophe, Eslami, Aida, Lamothe, Jennifer, Gaudreault, Nathalie, Joubert, Philippe, Obeidat, Ma’en, van den Berge, Maarten, Timens, Wim, Sin, Don D., Nickle, David C., Hao, Ke, Labbé, Catherine, Godbout, Krystelle, Côté, Andréanne, Laviolette, Michel, Boulet, Louis-Philippe, Mathieu, Patrick, Thériault, Sébastien, Bossé, Yohan
Publicado no Commun Biol (2021)

Genetic Variation in LPA, Calcific Aortic Valve Stenosis in Patients Undergoing Cardiac Surgery, and Familial Risk of Aortic Valve Microcalcification

por Perrot, Nicolas, Thériault, Sébastien, Dina, Christian, Chen, Hao Yu, Boekholdt, S. Matthijs, Rigade, Sidwell, Després, Audrey-Anne, Poulin, Anthony, Capoulade, Romain, Le Tourneau, Thierry, Messika-Zeitoun, David, Trottier, Mikaël, Tessier, Michel, Guimond, Jean, Nadeau, Maxime, Engert, James C., Khaw, Kay-Tee, Wareham, Nicholas J., Dweck, Marc R., Mathieu, Patrick, Pibarot, Philippe, Schott, Jean-Jacques, Thanassoulis, George, Clavel, Marie-Annick, Bossé, Yohan, Arsenault, Benoit J.
Publicado no JAMA Cardiol (2019)

Genetic and In Vitro Inhibition of PCSK9 and Calcific Aortic Valve Stenosis

por Perrot, Nicolas, Valerio, Vincenza, Moschetta, Donato, Boekholdt, S. Matthijs, Dina, Christian, Chen, Hao Yu, Abner, Erik, Martinsson, Andreas, Manikpurage, Hasanga D., Rigade, Sidwell, Capoulade, Romain, Mass, Elvira, Clavel, Marie-Annick, Le Tourneau, Thierry, Messika-Zeitoun, David, Wareham, Nicholas J., Engert, James C., Polvani, Gianluca, Pibarot, Philippe, Esko, Tõnu, Smith, J. Gustav, Mathieu, Patrick, Thanassoulis, George, Schott, Jean-Jacques, Bossé, Yohan, Camera, Marina, Thériault, Sébastien, Poggio, Paolo, Arsenault, Benoit J.
Publicado no JACC Basic Transl Sci (2020)

Genetic Susceptibility for Atrial Fibrillation in Patients Undergoing Atrial Fibrillation Ablation

por Shoemaker, M. Benjamin, Husser, Daniela, Roselli, Carolina, Jazairi, Meelad Al, Chrispin, Jonathan, Kühne, Michael, Neumann, Benjamin, Knight, Stacey, Sun, Han, Mohanty, Sanghamitra, Shaffer, Christian, Thériault, Sébastien, Rinke, Lauren Lee, Siland, Joylene E., Crawford, Diane M., Ueberham, Laura, Zardkoohi, Omeed, Büttner, Petra, Geelhoed, Bastiaan, Blum, Steffen, Aeschbacher, Stefanie, Smith, Jonathan D., Van Wagoner, David R., Freudling, Rebecca, Müller-Nurasyid, Martina, Montgomery, Jay, Yoneda, Zachary, Wells, Quinn, Issa, Tariq, Weeke, Peter, Jacobs, Victoria, Van Gelder, Isabelle C., Hindricks, Gerhard, Barnard, John, Calkins, Hugh, Darbar, Dawood, Michaud, Greg, Kääb, Stefan, Ellinor, Patrick, Natale, Andrea, Chung, Mina, Nazarian, Saman, Cutler, Michael J., Sinner, Moritz F., Conen, David, Rienstra, Michiel, Bollmann, Andreas, Roden, Dan M., Lubitz, Steven
Publicado no Circ Arrhythm Electrophysiol (2020)

Association of FADS1/2 Locus Variants and Polyunsaturated Fatty Acids With Aortic Stenosis

por Chen, Hao Yu, Cairns, Benjamin J., Small, Aeron M., Burr, Hannah A., Ambikkumar, Athithan, Martinsson, Andreas, Thériault, Sébastien, Munter, Hans Markus, Steffen, Brian, Zhang, Richard, Levinson, Rebecca T., Shaffer, Christian M., Rong, Jian, Sonestedt, Emily, Dufresne, Line, Ljungberg, Johan, Näslund, Ulf, Johansson, Bengt, Ranatunga, Dilrini K., Whitmer, Rachel A., Budoff, Matthew J., Nguyen, Albert, Vasan, Ramachandran S., Larson, Martin G., Harris, William S., Damrauer, Scott M., Stark, Ken D., Boekholdt, S. Matthijs, Wareham, Nicholas J., Pibarot, Philippe, Arsenault, Benoit J., Mathieu, Patrick, Gudnason, Vilmundur, O’Donnell, Christopher J., Rotter, Jerome I., Tsai, Michael Y., Post, Wendy S., Clarke, Robert, Söderberg, Stefan, Bossé, Yohan, Wells, Quinn S., Smith, J. Gustav, Rader, Daniel J., Lathrop, Mark, Engert, James C., Thanassoulis, George
Publicado no JAMA Cardiol (2020)

Genetic Interactions with Age, Sex, Body Mass Index, and Hypertension in Relation to Atrial Fibrillation: The AFGen Consortium

por Weng, Lu-Chen, Lunetta, Kathryn L., Müller-Nurasyid, Martina, Smith, Albert Vernon, Thériault, Sébastien, Weeke, Peter E., Barnard, John, Bis, Joshua C., Lyytikäinen, Leo-Pekka, Kleber, Marcus E., Martinsson, Andreas, Lin, Henry J., Rienstra, Michiel, Trompet, Stella, Krijthe, Bouwe P., Dörr, Marcus, Klarin, Derek, Chasman, Daniel I., Sinner, Moritz F., Waldenberger, Melanie, Launer, Lenore J., Harris, Tamara B., Soliman, Elsayed Z., Alonso, Alvaro, Paré, Guillaume, Teixeira, Pedro L., Denny, Joshua C., Shoemaker, M. Benjamin, Van Wagoner, David R., Smith, Jonathan D., Psaty, Bruce M., Sotoodehnia, Nona, Taylor, Kent D., Kähönen, Mika, Nikus, Kjell, Delgado, Graciela E., Melander, Olle, Engström, Gunnar, Yao, Jie, Guo, Xiuqing, Christophersen, Ingrid E., Ellinor, Patrick T., Geelhoed, Bastiaan, Verweij, Niek, Macfarlane, Peter, Ford, Ian, Heeringa, Jan, Franco, Oscar H., Uitterlinden, André G., Völker, Uwe, Teumer, Alexander, Rose, Lynda M., Kääb, Stefan, Gudnason, Vilmundur, Arking, Dan E., Conen, David, Roden, Dan M., Chung, Mina K., Heckbert, Susan R., Benjamin, Emelia J., Lehtimäki, Terho, März, Winfried, Smith, J. Gustav, Rotter, Jerome I., van der Harst, Pim, Jukema, J. Wouter, Stricker, Bruno H., Felix, Stephan B., Albert, Christine M., Lubitz, Steven A.
Publicado no Sci Rep (2017)

Novel alcohol-related genes suggest shared genetic mechanisms with neuropsychiatric disorders

por Evangelou, Evangelos, Gao, He, Chu, Congying, Ntritsos, Georgios, Blakeley, Paul, Butts, Andrew R, Pazoki, Raha, Suzuki, Hideaki, Koskeridis, Fotios, Yiorkas, Andrianos M, Karaman, Ibrahim, Elliott, Joshua, Luo, Qiang, Aeschbacher, Stefanie, Bartz, Traci M, Baumeister, Sebastian E, Braund, Peter S, Brown, Michael R, Brody, Jennifer A, Clarke, Toni-Kim, Dimou, Niki, Faul, Jessica D, Homuth, Georg, Jackson, Anne U, Kentistou, Katherine A, Joshi, Peter K, Lemaitre, Rozenn N, Lind, Penelope A, Lyytikäinen, Leo-Pekka, Mangino, Massimo, Milaneschi, Yuri, Nelson, Christopher P, Nolte, Ilja M, Perälä, Mia-Maria, Polasek, Ozren, Porteous, David, Ratliff, Scott M, Smith, Jennifer A, Stančáková, Alena, Teumer, Alexander, Tuominen, Samuli, Thériault, Sébastien, Vangipurapu, Jagadish, Whitfield, John B, Wood, Alexis, Yao, Jie, Yu, Bing, Zhao, Wei, Arking, Dan E, Auvinen, Juha, Liu, Chunyu, Männikkö, Minna, Risch, Lorenz, Rotter, Jerome I, Snieder, Harold, Veijola, Juha, Blakemore, Alexandra I, Boehnke, Michael, Campbell, Harry, Conen, David, Eriksson, Johan G, Grabe, Hans J, Guo, Xiuqing, van der Harst, Pim, Hartman, Catharina A, Hayward, Caroline, Heath, Andrew C, Jarvelin, Marjo-Riitta, Kähönen, Mika, Kardia, Sharon LR, Kühne, Michael, Kuusisto, Johanna, Laakso, Markku, Lahti, Jari, Lehtimäki, Terho, McIntosh, Andrew M, Mohlke, Karen L, Morrison, Alanna C, Martin, Nicholas G, Oldehinkel, Albertine J, Penninx, Brenda WJH, Psaty, Bruce M, Raitakari, Olli T, Rudan, Igor, Samani, Nilesh J, Scott, Laura J, Spector, Tim D, Verweij, Niek, Weir, David R, Wilson, James F, Levy, Daniel, Tzoulaki, Ioanna, Bell, Jimmy D, Matthews, Paul M., Rothenfluh, Adrian, Desrivières, Sylvane, Schumann, Gunter, Elliott, Paul
Publicado no Nat Hum Behav (2019)