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A Mendelian randomization study of IL6 signaling in cardiovascular diseases, immune-related disorders and longevity

Growing evidence suggests that inflammation is a significant contributor to different cardiovascular diseases (CVDs). Mendelian randomization (MR) was performed to assess the causal inference between plasma soluble IL6 receptor (sIL6R), a negative regulator of IL6 signaling, and different cardiovasc...

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Detalhes bibliográficos
Publicado no:NPJ Genom Med
Main Authors: Rosa, Mickael, Chignon, Arnaud, Li, Zhonglin, Boulanger, Marie-Chloé, Arsenault, Benoit J., Bossé, Yohan, Thériault, Sébastien, Mathieu, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6754413/
https://ncbi.nlm.nih.gov/pubmed/31552141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41525-019-0097-4
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