Effects of a community-based healthy heart program on increasing healthy women's physical activity: a randomized controlled trial guided by Community-based Participatory Research (...

Por Pazoki, Raha, Nabipour, Iraj, Seyednezami, Nasrin, Imami, Seyed Reza
Publicado em 2007

Genetic Basis of Ventricular Arrhythmias

Por Pazoki, Raha, Wilde, Arthur A. M., Bezzina, Connie R.
Publicado em 2010

The association of metabolic syndrome and Chlamydia pneumoniae, Helicobacter pylori, cytomegalovirus, and herpes simplex virus type 1: The Persian Gulf Healthy Heart Study

Por Nabipour, Iraj, Vahdat, Katayon, Jafari, Seyed Mojtaba, Pazoki, Raha, Sanjdideh, Zahra
Publicado em 2006

Oncogenic human papillomavirus genital infection in southern Iranian women: population-based study versus clinic-based data

Por Eghbali, Seyed Sajjad, Amirinejad, Roya, Obeidi, Narges, Mosadeghzadeh, Shiva, Vahdat, Katayoun, Azizi, Fatemeh, Pazoki, Raha, Sanjdideh, Zahra, Amiri, Zahra, Nabipour, Iraj, Zandi, Keivan
Publicado em 2012

SNPs Identified as Modulators of ECG Traits in the General Population Do Not Markedly Affect ECG Traits during Acute Myocardial Infarction nor Ventricular Fibrillation Risk in This...

Por Pazoki, Raha, de Jong, Jonas S.S.G., Marsman, Roos F., Bruinsma, Nienke, Dekker, Lukas R. C., Wilde, Arthur A. M., Bezzina, Connie R., Tanck, Michael W. T.
Publicado em 2013

The global impact of non-communicable diseases on macro-economic productivity: a systematic review

Por Chaker, Layal, Falla, Abby, van der Lee, Sven J., Muka, Taulant, Imo, David, Jaspers, Loes, Colpani, Veronica, Mendis, Shanthi, Chowdhury, Rajiv, Bramer, Wichor M., Pazoki, Raha, Franco, Oscar H.
Publicado no Eur J Epidemiol (2015)

No association between gluten sensitivity and amyotrophic lateral sclerosis

Por Visser, Anne E., Pazoki, Raha, Pulit, Sara L., van Rheenen, Wouter, Raaphorst, Joost, van der Kooi, Anneke J., Ricaño-Ponce, Isis, Wijmenga, Cisca, Otten, Henny G., Veldink, Jan H., van den Berg, Leonard H.
Publicado no J Neurol (2017)

Genome-wide association study identifies a susceptibility locus at 21q21 for ventricular fibrillation in acute myocardial infarction

Por Bezzina, Connie R, Pazoki, Raha, Bardai, Abdennasser, Marsman, Roos F, de Jong, Jonas S S G, Blom, Marieke T, Scicluna, Brendon P, Jukema, J Wouter, Bindraban, Navin R, Lichtner, Peter, Pfeufer, Arne, Bishopric, Nanette H, Roden, Dan M, Meitinger, Thomas, Chugh, Sumeet S, Myerburg, Robert J, Jouven, Xavier, Kääb, Stefan, Dekker, Lukas R C, Tan, Hanno L, Tanck, Michael W T, Wilde, Arthur A M
Publicado em 2010

Whole-Exome Sequencing Identifies Loci Associated with Blood Cell Traits and Reveals a Role for Alternative GFI1B Splice Variants in Human Hematopoiesis

Por Polfus, Linda M., Khajuria, Rajiv K., Schick, Ursula M., Pankratz, Nathan, Pazoki, Raha, Brody, Jennifer A., Chen, Ming-Huei, Auer, Paul L., Floyd, James S., Huang, Jie, Lange, Leslie, van Rooij, Frank J.A., Gibbs, Richard A., Metcalf, Ginger, Muzny, Donna, Veeraraghavan, Narayanan, Walter, Klaudia, Chen, Lu, Yanek, Lisa, Becker, Lewis C., Peloso, Gina M., Wakabayashi, Aoi, Kals, Mart, Metspalu, Andres, Esko, Tõnu, Fox, Keolu, Wallace, Robert, Franceshini, Nora, Matijevic, Nena, Rice, Kenneth M., Bartz, Traci M., Lyytikäinen, Leo-Pekka, Kähönen, Mika, Lehtimäki, Terho, Raitakari, Olli T., Li-Gao, Ruifang, Mook-Kanamori, Dennis O., Lettre, Guillaume, van Duijn, Cornelia M., Franco, Oscar H., Rich, Stephen S., Rivadeneira, Fernando, Hofman, Albert, Uitterlinden, André G., Wilson, James G., Psaty, Bruce M., Soranzo, Nicole, Dehghan, Abbas, Boerwinkle, Eric, Zhang, Xiaoling, Johnson, Andrew D., O’Donnell, Christopher J., Johnsen, Jill M., Reiner, Alexander P., Ganesh, Santhi K., Sankaran, Vijay G.
Publicado no Am J Hum Genet (2016)

Whole-Exome Sequencing Identifies Loci Associated with Blood Cell Traits and Reveals a Role for Alternative GFI1B Splice Variants in Human Hematopoiesis

Por Polfus, Linda M., Khajuria, Rajiv K., Schick, Ursula M., Pankratz, Nathan, Pazoki, Raha, Brody, Jennifer A., Chen, Ming-Huei, Auer, Paul L., Floyd, James S., Huang, Jie, Lange, Leslie, van Rooij, Frank J.A., Gibbs, Richard A., Metcalf, Ginger, Muzny, Donna, Veeraraghavan, Narayanan, Walter, Klaudia, Chen, Lu, Yanek, Lisa, Becker, Lewis C., Peloso, Gina M., Wakabayashi, Aoi, Kals, Mart, Metspalu, Andres, Esko, Tõnu, Fox, Keolu, Wallace, Robert, Franceschini, Nora, Matijevic, Nena, Rice, Kenneth M., Bartz, Traci M., Lyytikäinen, Leo-Pekka, Kähönen, Mika, Lehtimäki, Terho, Raitakari, Olli T., Li-Gao, Ruifang, Mook-Kanamori, Dennis O., Lettre, Guillaume, van Duijn, Cornelia M., Franco, Oscar H., Rich, Stephen S., Rivadeneira, Fernando, Hofman, Albert, Uitterlinden, André G., Wilson, James G., Psaty, Bruce M., Soranzo, Nicole, Dehghan, Abbas, Boerwinkle, Eric, Zhang, Xiaoling, Johnson, Andrew D., O’Donnell, Christopher J., Johnsen, Jill M., Reiner, Alexander P., Ganesh, Santhi K., Sankaran, Vijay G.
Publicado no Am J Hum Genet (2016)

Identification of a Sudden Cardiac Death Susceptibility Locus at 2q24.2 through Genome-Wide Association in European Ancestry Individuals

Por Arking, Dan E., Junttila, M. Juhani, Goyette, Philippe, Huertas-Vazquez, Adriana, Eijgelsheim, Mark, Blom, Marieke T., Newton-Cheh, Christopher, Reinier, Kyndaron, Teodorescu, Carmen, Uy-Evanado, Audrey, Carter-Monroe, Naima, Kaikkonen, Kari S., Kortelainen, Marja-Leena, Boucher, Gabrielle, Lagacé, Caroline, Moes, Anna, Zhao, XiaoQing, Kolodgie, Frank, Rivadeneira, Fernando, Hofman, Albert, Witteman, Jacqueline C. M., Uitterlinden, André G., Marsman, Roos F., Pazoki, Raha, Bardai, Abdennasser, Koster, Rudolph W., Dehghan, Abbas, Hwang, Shih-Jen, Bhatnagar, Pallav, Post, Wendy, Hilton, Gina, Prineas, Ronald J., Li, Man, Köttgen, Anna, Ehret, Georg, Boerwinkle, Eric, Coresh, Josef, Kao, W. H. Linda, Psaty, Bruce M., Tomaselli, Gordon F., Sotoodehnia, Nona, Siscovick, David S., Burke, Greg L., Marbán, Eduardo, Spooner, Peter M., Cupples, L. Adrienne, Jui, Jonathan, Gunson, Karen, Kesäniemi, Y. Antero, Wilde, Arthur A. M., Tardif, Jean-Claude, O'Donnell, Christopher J., Bezzina, Connie R., Virmani, Renu, Stricker, Bruno H. C. h., Tan, Hanno L., Albert, Christine M., Chakravarti, Aravinda, Rioux, John D., Huikuri, Heikki V., Chugh, Sumeet S.
Publicado em 2011

Discovery and refinement of genetic loci associated with cardiometabolic risk using dense imputation maps

Por Iotchkova, Valentina, Huang, Jie, Morris, John A., Jain, Deepti, Barbieri, Caterina, Walter, Klaudia, Min, Josine L., Chen, Lu, Astle, William, Cocca, Massimilian, Deelen, Patrick, Elding, Heather, Farmaki, Aliki-Eleni, Franklin, Christopher S., Franberg, Mattias, Gaunt, Tom R., Hofman, Albert, Jiang, Tao, Kleber, Marcus E., Lachance, Genevieve, Luan, Jian'an, Malerba, Giovanni, Matchan, Angela, Mead, Daniel, Memari, Yasin, Ntalla, Ioanna, Panoutsopoulou, Kalliope, Pazoki, Raha, Perry, John R.B., Rivadeneira, Fernando, Sabater-Lleal, Maria, Sennblad, Bengt, Shin, So-Youn, Southam, Lorraine, Traglia, Michela, van Dijk, Freerk, van Leeuwen, Elisabeth M., Zaza, Gianluigi, Zhang, Weihua, Amin, Najaf, Butterworth, Adam, Chambers, John C., Dedoussis, George, Dehghan, Abbas, Franco, Oscar H., Franke, Lude, Frontini, Mattia, Gambaro, Giovanni, Gasparini, Paolo, Hamsten, Anders, Issacs, Aaron, Kooner, Jaspal S., Kooperberg, Charles, Langenberg, Claudia, Marz, Winfried, Scott, Robert A., Swertz, Morris A., Toniolo, Daniela, Uitterlinden, Andre G., van Duijn, Cornelia M., Watkins, Hugh, Zeggini, Eleftheria, Maurano, Mathew T., Timpson, Nicholas J., Reiner, Alexander P., Auer, Paul L., Soranzo, Nicole
Publicado no Nat Genet (2016)

Meta-analysis of rare and common exome chip variants identifies S1PR4 and other loci influencing blood cell traits

Por Pankratz, Nathan, Schick, Ursula M, Zhou, Yi, Zhou, Wei, Ahluwalia, Tarunveer Singh, Allende, Maria Laura, Auer, Paul L, Bork-Jensen, Jette, Brody, Jennifer A, Chen, Ming-Huei, Clavo, Vinna, Eicher, John D, Grarup, Niels, Hagedorn, Elliott J, Hu, Bella, Hunker, Kristina, Johnson, Andrew D, Leusink, Maarten, Lu, Yingchang, Lyytikäinen, Leo-Pekka, Manichaikul, Ani, Marioni, Riccardo E, Nalls, Mike A, Pazoki, Raha, Smith, Albert Vernon, van Rooij, Frank J A, Yang, Min-Lee, Zhang, Xiaoling, Zhang, Yan, Asselbergs, Folkert W, Boerwinkle, Eric, Borecki, Ingrid B, Bottinger, Erwin P, Cushman, Mary, de Bakker, Paul I W, Deary, Ian J, Dong, Liguang, Feitosa, Mary F, Floyd, James S, Franceschini, Nora, Franco, Oscar H, Garcia, Melissa E, Grove, Megan L, Gudnason, Vilmundur, Hansen, Torben, Harris, Tamara B, Hofman, Albert, Jackson, Rebecca D, Jia, Jia, Kähönen, Mika, Launer, Lenore J, Lehtimäki, Terho, Liewald, David C, Linneberg, Allan, Liu, Yongmei, Loos, Ruth J F, Nguyen, Vy M, Numans, Mattijs E, Pedersen, Oluf, Psaty, Bruce M, Raitakari, Olli T, Rich, Stephen S, Rivadeneira, Fernando, Di Sant, Amanda M Rosa, Rotter, Jerome I, Starr, John M, Taylor, Kent D, Thuesen, Betina Heinsbæk, Tracy, Russell P, Uitterlinden, Andre G, Wang, Jiansong, Wang, Judy, Dehghan, Abbas, Huo, Yong, Cupples, L Adrienne, Wilson, James G, Proia, Richard L, Zon, Leonard I, O’Donnell, Christopher J, Reiner, Alex P, Ganesh, Santhi K
Publicado no Nat Genet (2016)

Large-Scale Exome-wide Association Analysis Identifies Loci for White Blood Cell Traits and Pleiotropy with Immune-Mediated Diseases

Por Tajuddin, Salman M., Schick, Ursula M., Eicher, John D., Chami, Nathalie, Giri, Ayush, Brody, Jennifer A., Hill, W. David, Kacprowski, Tim, Li, Jin, Lyytikäinen, Leo-Pekka, Manichaikul, Ani, Mihailov, Evelin, O’Donoghue, Michelle L., Pankratz, Nathan, Pazoki, Raha, Polfus, Linda M., Smith, Albert Vernon, Schurmann, Claudia, Vacchi-Suzzi, Caterina, Waterworth, Dawn M., Evangelou, Evangelos, Yanek, Lisa R., Burt, Amber, Chen, Ming-Huei, van Rooij, Frank J.A., Floyd, James S., Greinacher, Andreas, Harris, Tamara B., Highland, Heather M., Lange, Leslie A., Liu, Yongmei, Mägi, Reedik, Nalls, Mike A., Mathias, Rasika A., Nickerson, Deborah A., Nikus, Kjell, Starr, John M., Tardif, Jean-Claude, Tzoulaki, Ioanna, Velez Edwards, Digna R., Wallentin, Lars, Bartz, Traci M., Becker, Lewis C., Denny, Joshua C., Raffield, Laura M., Rioux, John D., Friedrich, Nele, Fornage, Myriam, Gao, He, Hirschhorn, Joel N., Liewald, David C.M., Rich, Stephen S., Uitterlinden, Andre, Bastarache, Lisa, Becker, Diane M., Boerwinkle, Eric, de Denus, Simon, Bottinger, Erwin P., Hayward, Caroline, Hofman, Albert, Homuth, Georg, Lange, Ethan, Launer, Lenore J., Lehtimäki, Terho, Lu, Yingchang, Metspalu, Andres, O’Donnell, Chris J., Quarells, Rakale C., Richard, Melissa, Torstenson, Eric S., Taylor, Kent D., Vergnaud, Anne-Claire, Zonderman, Alan B., Crosslin, David R., Deary, Ian J., Dörr, Marcus, Elliott, Paul, Evans, Michele K., Gudnason, Vilmundur, Kähönen, Mika, Psaty, Bruce M., Rotter, Jerome I., Slater, Andrew J., Dehghan, Abbas, White, Harvey D., Ganesh, Santhi K., Loos, Ruth J.F., Esko, Tõnu, Faraday, Nauder, Wilson, James G., Cushman, Mary, Johnson, Andrew D., Edwards, Todd L., Zakai, Neil A., Lettre, Guillaume, Reiner, Alex P., Auer, Paul L.
Publicado no Am J Hum Genet (2016)

Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits

Por Chami, Nathalie, Chen, Ming-Huei, Slater, Andrew J., Eicher, John D., Evangelou, Evangelos, Tajuddin, Salman M., Love-Gregory, Latisha, Kacprowski, Tim, Schick, Ursula M., Nomura, Akihiro, Giri, Ayush, Lessard, Samuel, Brody, Jennifer A., Schurmann, Claudia, Pankratz, Nathan, Yanek, Lisa R., Manichaikul, Ani, Pazoki, Raha, Mihailov, Evelin, Hill, W. David, Raffield, Laura M., Burt, Amber, Bartz, Traci M., Becker, Diane M., Becker, Lewis C., Boerwinkle, Eric, Bork-Jensen, Jette, Bottinger, Erwin P., O’Donoghue, Michelle L., Crosslin, David R., de Denus, Simon, Dubé, Marie-Pierre, Elliott, Paul, Engström, Gunnar, Evans, Michele K., Floyd, James S., Fornage, Myriam, Gao, He, Greinacher, Andreas, Gudnason, Vilmundur, Hansen, Torben, Harris, Tamara B., Hayward, Caroline, Hernesniemi, Jussi, Highland, Heather M., Hirschhorn, Joel N., Hofman, Albert, Irvin, Marguerite R., Kähönen, Mika, Lange, Ethan, Launer, Lenore J., Lehtimäki, Terho, Li, Jin, Liewald, David C.M., Linneberg, Allan, Liu, Yongmei, Lu, Yingchang, Lyytikäinen, Leo-Pekka, Mägi, Reedik, Mathias, Rasika A., Melander, Olle, Metspalu, Andres, Mononen, Nina, Nalls, Mike A., Nickerson, Deborah A., Nikus, Kjell, O’Donnell, Chris J., Orho-Melander, Marju, Pedersen, Oluf, Petersmann, Astrid, Polfus, Linda, Psaty, Bruce M., Raitakari, Olli T., Raitoharju, Emma, Richard, Melissa, Rice, Kenneth M., Rivadeneira, Fernando, Rotter, Jerome I., Schmidt, Frank, Smith, Albert Vernon, Starr, John M., Taylor, Kent D., Teumer, Alexander, Thuesen, Betina H., Torstenson, Eric S., Tracy, Russell P., Tzoulaki, Ioanna, Zakai, Neil A., Vacchi-Suzzi, Caterina, van Duijn, Cornelia M., van Rooij, Frank J.A., Cushman, Mary, Deary, Ian J., Velez Edwards, Digna R., Vergnaud, Anne-Claire, Wallentin, Lars, Waterworth, Dawn M., White, Harvey D., Wilson, James G., Zonderman, Alan B., Kathiresan, Sekar, Grarup, Niels, Esko, Tõnu, Loos, Ruth J.F., Lange, Leslie A., Faraday, Nauder, Abumrad, Nada A., Edwards, Todd L., Ganesh, Santhi K., Auer, Paul L., Johnson, Andrew D., Reiner, Alexander P., Lettre, Guillaume
Publicado no Am J Hum Genet (2016)

Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals

Por Eicher, John D., Chami, Nathalie, Kacprowski, Tim, Nomura, Akihiro, Chen, Ming-Huei, Yanek, Lisa R., Tajuddin, Salman M., Schick, Ursula M., Slater, Andrew J., Pankratz, Nathan, Polfus, Linda, Schurmann, Claudia, Giri, Ayush, Brody, Jennifer A., Lange, Leslie A., Manichaikul, Ani, Hill, W. David, Pazoki, Raha, Elliot, Paul, Evangelou, Evangelos, Tzoulaki, Ioanna, Gao, He, Vergnaud, Anne-Claire, Mathias, Rasika A., Becker, Diane M., Becker, Lewis C., Burt, Amber, Crosslin, David R., Lyytikäinen, Leo-Pekka, Nikus, Kjell, Hernesniemi, Jussi, Kähönen, Mika, Raitoharju, Emma, Mononen, Nina, Raitakari, Olli T., Lehtimäki, Terho, Cushman, Mary, Zakai, Neil A., Nickerson, Deborah A., Raffield, Laura M., Quarells, Rakale, Willer, Cristen J., Peloso, Gina M., Abecasis, Goncalo R., Liu, Dajiang J., Deloukas, Panos, Samani, Nilesh J., Schunkert, Heribert, Erdmann, Jeanette, Fornage, Myriam, Richard, Melissa, Tardif, Jean-Claude, Rioux, John D., Dube, Marie-Pierre, de Denus, Simon, Lu, Yingchang, Bottinger, Erwin P., Loos, Ruth J.F., Smith, Albert Vernon, Harris, Tamara B., Launer, Lenore J., Gudnason, Vilmundur, Velez Edwards, Digna R., Torstenson, Eric S., Liu, Yongmei, Tracy, Russell P., Rotter, Jerome I., Rich, Stephen S., Highland, Heather M., Boerwinkle, Eric, Li, Jin, Lange, Ethan, Wilson, James G., Mihailov, Evelin, Mägi, Reedik, Hirschhorn, Joel, Metspalu, Andres, Esko, Tõnu, Vacchi-Suzzi, Caterina, Nalls, Mike A., Zonderman, Alan B., Evans, Michele K., Engström, Gunnar, Orho-Melander, Marju, Melander, Olle, O’Donoghue, Michelle L., Waterworth, Dawn M., Wallentin, Lars, White, Harvey D., Floyd, James S., Bartz, Traci M., Rice, Kenneth M., Psaty, Bruce M., Starr, J.M., Liewald, David C.M., Hayward, Caroline, Deary, Ian J., Greinacher, Andreas, Völker, Uwe, Thiele, Thomas, Völzke, Henry, van Rooij, Frank J.A., Uitterlinden, André G., Franco, Oscar H., Dehghan, Abbas, Edwards, Todd L., Ganesh, Santhi K., Kathiresan, Sekar, Faraday, Nauder, Auer, Paul L., Reiner, Alex P., Lettre, Guillaume, Johnson, Andrew D.
Publicado no Am J Hum Genet (2016)

PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study

Por Schmidt, Amand F, Swerdlow, Daniel I, Holmes, Michael V, Patel, Riyaz S, Fairhurst-Hunter, Zammy, Lyall, Donald M, Hartwig, Fernando Pires, Horta, Bernardo Lessa, Hyppönen, Elina, Power, Christine, Moldovan, Max, van Iperen, Erik, Hovingh, G Kees, Demuth, Ilja, Norman, Kristina, Steinhagen-Thiessen, Elisabeth, Demuth, Juri, Bertram, Lars, Liu, Tian, Coassin, Stefan, Willeit, Johann, Kiechl, Stefan, Willeit, Karin, Mason, Dan, Wright, John, Morris, Richard, Wanamethee, Goya, Whincup, Peter, Ben-Shlomo, Yoav, McLachlan, Stela, Price, Jackie F, Kivimaki, Mika, Welch, Catherine, Sanchez-Galvez, Adelaida, Marques-Vidal, Pedro, Nicolaides, Andrew, Panayiotou, Andrie G, Onland-Moret, N Charlotte, van der Schouw, Yvonne T, Matullo, Giuseppe, Fiorito, Giovanni, Guarrera, Simonetta, Sacerdote, Carlotta, Wareham, Nicholas J, Langenberg, Claudia, Scott, Robert, Luan, Jian'an, Bobak, Martin, Malyutina, Sofia, Pająk, Andrzej, Kubinova, Ruzena, Tamosiunas, Abdonas, Pikhart, Hynek, Husemoen, Lise Lotte Nystrup, Grarup, Niels, Pedersen, Oluf, Hansen, Torben, Linneberg, Allan, Simonsen, Kenneth Starup, Cooper, Jackie, Humphries, Steve E, Brilliant, Murray, Kitchner, Terrie, Hakonarson, Hakon, Carrell, David S, McCarty, Catherine A, Kirchner, H Lester, Larson, Eric B, Crosslin, David R, de Andrade, Mariza, Roden, Dan M, Denny, Joshua C, Carty, Cara, Hancock, Stephen, Attia, John, Holliday, Elizabeth, O'Donnell, Martin, Yusuf, Salim, Chong, Michael, Pare, Guillaume, van der Harst, Pim, Said, M Abdullah, Eppinga, Ruben N, Verweij, Niek, Snieder, Harold, Christen, Tim, Mook-Kanamori, Dennis O, Gustafsson, Stefan, Lind, Lars, Ingelsson, Erik, Pazoki, Raha, Franco, Oscar, Hofman, Albert, Uitterlinden, Andre, Dehghan, Abbas, Teumer, Alexander, Baumeister, Sebastian, Dörr, Marcus, Lerch, Markus M, Völker, Uwe, Völzke, Henry, Ward, Joey, Pell, Jill P, Smith, Daniel J, Meade, Tom, Maitland-van der Zee, Anke H, Baranova, Ekaterina V, Young, Robin, Ford, Ian, Campbell, Archie, Padmanabhan, Sandosh, Bots, Michiel L, Grobbee, Diederick E, Froguel, Philippe, Thuillier, Dorothée, Balkau, Beverley, Bonnefond, Amélie, Cariou, Bertrand, Smart, Melissa, Bao, Yanchun, Kumari, Meena, Mahajan, Anubha, Ridker, Paul M, Chasman, Daniel I, Reiner, Alex P, Lange, Leslie A, Ritchie, Marylyn D, Asselbergs, Folkert W, Casas, Juan-Pablo, Keating, Brendan J, Preiss, David, Hingorani, Aroon D, Sattar, Naveed
Publicado no Lancet Diabetes Endocrinol (2017)