Pathways to understanding the genomic aetiology of osteoarthritis

di Cibrián Uhalte, Elena, Wilkinson, Jeremy Mark, Southam, Lorraine, Zeggini, Eleftheria
Pubblicato in Hum Mol Genet (2017)

Association of a functional microsatellite within intron 1 of the BMP5 gene with susceptibility to osteoarthritis

di Wilkins, James M, Southam, Lorraine, Mustafa, Zehra, Chapman, Kay, Loughlin, John
Pubblicazione 2009

Replication of Established Common Genetic Variants for Adult BMI and Childhood Obesity in Greek Adolescents: The TEENAGE Study

di Ntalla, Ioanna, Panoutsopoulou, Kalliope, Vlachou, Panagiota, Southam, Lorraine, William Rayner, Nigel, Zeggini, Eleftheria, Dedoussis, George V
Pubblicazione 2013

Very low-depth sequencing in a founder population identifies a cardioprotective APOC3 signal missed by genome-wide imputation

di Gilly, Arthur, Ritchie, Graham Rs, Southam, Lorraine, Farmaki, Aliki-Eleni, Tsafantakis, Emmanouil, Dedoussis, George, Zeggini, Eleftheria
Pubblicato in Hum Mol Genet (2016)

Functional variants within the secreted frizzled-related protein 3 gene are associated with hip osteoarthritis in females

di Loughlin, John, Dowling, Barbara, Chapman, Kay, Marcelline, Lucy, Mustafa, Zehra, Southam, Lorraine, Ferreira, Athena, Ciesielski, Cathleen, Carson, Dennis A., Corr, Maripat
Pubblicazione 2004

Functional Analysis of the Osteoarthritis Susceptibility–Associated GDF5 Regulatory Polymorphism

di Egli, Rainer J., Southam, Lorraine, Wilkins, James M., Lorenzen, Inken, Pombo-Suarez, Manuel, Gonzalez, Antonio, Carr, Andrew, Chapman, Kay, Loughlin, John
Pubblicato in Arthritis Rheum (2009)

Linkage and Association Analysis of Angiotensin I–Converting Enzyme (ACE)–Gene Polymorphisms with ACE Concentration and Blood Pressure

di Zhu, Xiaofeng, Bouzekri, Nourdine, Southam, Lorraine, Cooper, Richard S., Adeyemo, Adebowale, McKenzie, Colin A., Luke, Amy, Chen, Guangjie, Elston, Robert C., Ward, Ryk
Pubblicazione 2001

Widespread epigenomic, transcriptomic and proteomic differences between hip osteophytic and articular chondrocytes in osteoarthritis

di Steinberg, Julia, Brooks, Roger A, Southam, Lorraine, Bhatnagar, Sahir, Roumeliotis, Theodoros I, Hatzikotoulas, Konstantinos, Zengini, Eleni, Wilkinson, J Mark, Choudhary, Jyoti S, McCaskie, Andrew W, Zeggini, Eleftheria
Pubblicato in Rheumatology (Oxford) (2018)

Whole genome sequencing and imputation in isolated populations identify genetic associations with medically-relevant complex traits

di Southam, Lorraine, Gilly, Arthur, Süveges, Dániel, Farmaki, Aliki-Eleni, Schwartzentruber, Jeremy, Tachmazidou, Ioanna, Matchan, Angela, Rayner, Nigel W., Tsafantakis, Emmanouil, Karaleftheri, Maria, Xue, Yali, Dedoussis, George, Zeggini, Eleftheria
Pubblicato in Nat Commun (2017)

The 2018 Otto Aufranc Award: How Does Genome-wide Variation Affect Osteolysis Risk After THA?

di MacInnes, Scott J., Hatzikotoulas, Konstantinos, Fenstad, Anne Marie, Shah, Karan, Southam, Lorraine, Tachmazidou, Ioanna, Hallan, Geir, Dale, Hårvard, Panoutsopoulou, Kalliope, Furnes, Ove, Zeggini, Eleftheria, Wilkinson, J. Mark
Pubblicato in Clin Orthop Relat Res (2019)

Erratum to: The 2018 Otto Aufranc Award: How Does Genome-wide Variation Affect Osteolysis Risk After THA?

di MacInnes, Scott J., Hatzikotoulas, Konstantinos, Fenstad, Anne Marie, Shah, Karan, Southam, Lorraine, Tachmazidou, Ioanna, Hallan, Geir, Dale, Hårvard, Panoutsopoulou, Kalliope, Furnes, Ove, Zeggini, Eleftheria, Wilkinson, J. Mark
Pubblicato in Clin Orthop Relat Res (2019)

Using ancestry-informative markers to identify fine structure across 15 populations of European origin

di Huckins, Laura M, Boraska, Vesna, Franklin, Christopher S, Floyd, James A B, Southam, Lorraine, Sullivan, Patrick F, Bulik, Cynthia M, Collier, David A, Tyler-Smith, Chris, Zeggini, Eleftheria, Tachmazidou, Ioanna
Pubblicazione 2014

Linking chondrocyte and synovial transcriptional profile to clinical phenotype in osteoarthritis

di Steinberg, Julia, Southam, Lorraine, Fontalis, Andreas, Clark, Matthew J, Jayasuriya, Raveen L, Swift, Diane, Shah, Karan M, Brooks, Roger A, McCaskie, Andrew W, Wilkinson, Jeremy Mark, Zeggini, Eleftheria
Pubblicato in Ann Rheum Dis (2021)

Whole-genome sequencing analysis of the cardiometabolic proteome

di Gilly, Arthur, Park, Young-Chan, Png, Grace, Barysenka, Andrei, Fischer, Iris, Bjørnland, Thea, Southam, Lorraine, Suveges, Daniel, Neumeyer, Sonja, Rayner, N. William, Tsafantakis, Emmanouil, Karaleftheri, Maria, Dedoussis, George, Zeggini, Eleftheria
Pubblicato in Nat Commun (2020)

Familial Hypercholesterolemia and Type 2 Diabetes in the Old Order Amish

di Xu, Huichun, Ryan, Kathleen A., Jaworek, Thomas J., Southam, Lorraine, Reid, Jeffrey G., Overton, John D., Baras, Aris, Puurunen, Marja K., Zeggini, Eleftheria, Taylor, Simeon I., Shuldiner, Alan R., Mitchell, Braxton D.
Pubblicato in Diabetes (2017)

A Genome-wide Association Study of Dupuytren Disease Reveals 17 Additional Variants Implicated in Fibrosis

di Ng, Michael, Thakkar, Dipti, Southam, Lorraine, Werker, Paul, Ophoff, Roel, Becker, Kerstin, Nothnagel, Michael, Franke, Andre, Nürnberg, Peter, Espirito-Santo, Ana Isabel, Izadi, David, Hennies, Hans Christian, Nanchahal, Jagdeep, Zeggini, Eleftheria, Furniss, Dominic
Pubblicato in Am J Hum Genet (2017)

Radiographic endophenotyping in hip osteoarthritis improves the precision of genetic association analysis

di Panoutsopoulou, Kalliope, Thiagarajah, Shankar, Zengini, Eleni, Day-Williams, Aaron G, Ramos, Yolande FM, Meessen, Jennifer MTA, Huetink, Kasper, Nelissen, Rob GHH, Southam, Lorraine, Rayner, N William, Doherty, Michael, Meulenbelt, Ingrid, Zeggini, Eleftheria, Wilkinson, J Mark
Pubblicato in Ann Rheum Dis (2017)

Evaluating the glucose raising effect of established loci via a genetic risk score

di Marouli, Eirini, Kanoni, Stavroula, Mamakou, Vasiliki, Hackinger, Sophie, Southam, Lorraine, Prins, Bram, Rentari, Angela, Dimitriou, Maria, Zengini, Eleni, Gonidakis, Fragiskos, Kolovou, Genovefa, Kontaxakis, Vassilis, Rallidis, Loukianos, Tentolouris, Nikolaos, Thanopoulou, Anastasia, Lamnissou, Klea, Dedoussis, George, Zeggini, Eleftheria, Deloukas, Panagiotis
Pubblicato in PLoS One (2017)

Very low-depth whole-genome sequencing in complex trait association studies

di Gilly, Arthur, Southam, Lorraine, Suveges, Daniel, Kuchenbaecker, Karoline, Moore, Rachel, Melloni, Giorgio E M, Hatzikotoulas, Konstantinos, Farmaki, Aliki-Eleni, Ritchie, Graham, Schwartzentruber, Jeremy, Danecek, Petr, Kilian, Britt, Pollard, Martin O, Ge, Xiangyu, Tsafantakis, Emmanouil, Dedoussis, George, Zeggini, Eleftheria
Pubblicato in Bioinformatics (2019)

Genome-wide association of phenotypes based on clustering patterns of hand osteoarthritis identify WNT9A as novel osteoarthritis gene

di Boer, Cindy Germaine, Yau, Michelle S, Rice, Sarah J, Coutinho de Almeida, Rodrigo, Cheung, Kathleen, Styrkarsdottir, Unnur, Southam, Lorraine, Broer, Linda, Wilkinson, Jeremy Mark, Uitterlinden, André G, Zeggini, Eleftheria, Felson, David, Loughlin, John, Young, Mariel, Capellini, Terence Dante, Meulenbelt, Ingrid, van Meurs, Joyce BJ
Pubblicato in Ann Rheum Dis (2021)