A carregar...

Very low-depth sequencing in a founder population identifies a cardioprotective APOC3 signal missed by genome-wide imputation

Cohort-wide very low-depth whole-genome sequencing (WGS) can comprehensively capture low-frequency sequence variation for the cost of a dense genome-wide genotyping array. Here, we analyse 1x sequence data across the APOC3 gene in a founder population from the island of Crete in Greece (n = 1239) an...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Gilly, Arthur, Ritchie, Graham Rs, Southam, Lorraine, Farmaki, Aliki-Eleni, Tsafantakis, Emmanouil, Dedoussis, George, Zeggini, Eleftheria
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5081052/
https://ncbi.nlm.nih.gov/pubmed/27146844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddw088
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!