Radiographic endophenotyping in hip osteoarthritis improves the precision of genetic association analysis

OBJECTIVE: Osteoarthritis (OA) has a strong genetic component but the success of previous genome-wide association studies (GWAS) has been restricted due to insufficient sample sizes and phenotype heterogeneity. Our aim was to examine the effect of clinically relevant endophenotyping according to sit...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Ann Rheum Dis
Main Authors: Panoutsopoulou, Kalliope, Thiagarajah, Shankar, Zengini, Eleni, Day-Williams, Aaron G, Ramos, Yolande FM, Meessen, Jennifer MTA, Huetink, Kasper, Nelissen, Rob GHH, Southam, Lorraine, Rayner, N William, Doherty, Michael, Meulenbelt, Ingrid, Zeggini, Eleftheria, Wilkinson, J Mark
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2017
Assuntos:
Clinical and Epidemiological Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5530347/
https://ncbi.nlm.nih.gov/pubmed/27974301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2016-210373
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados