Radiographic endophenotyping in hip osteoarthritis improves the precision of genetic association analysis

OBJECTIVE: Osteoarthritis (OA) has a strong genetic component but the success of previous genome-wide association studies (GWAS) has been restricted due to insufficient sample sizes and phenotype heterogeneity. Our aim was to examine the effect of clinically relevant endophenotyping according to sit...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Ann Rheum Dis
Autors principals: Panoutsopoulou, Kalliope, Thiagarajah, Shankar, Zengini, Eleni, Day-Williams, Aaron G, Ramos, Yolande FM, Meessen, Jennifer MTA, Huetink, Kasper, Nelissen, Rob GHH, Southam, Lorraine, Rayner, N William, Doherty, Michael, Meulenbelt, Ingrid, Zeggini, Eleftheria, Wilkinson, J Mark
Format: Artigo
Idioma:Inglês
Publicat: BMJ Publishing Group 2017
Matèries:
Clinical and Epidemiological Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5530347/
https://ncbi.nlm.nih.gov/pubmed/27974301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2016-210373
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars