Genome-Wide Association Studies: Contribution of Genomics to Understanding Blood Pressure and Essential Hypertension

Por Ehret, Georg B.
Publicado em 2010

The Contribution of the Framingham Heart Study to Gene Identification for Cardiovascular Risk Factors and Coronary Heart Disease

Por Ehret, Georg B.
Publicado em 2013

Genes for blood pressure: an opportunity to understand hypertension

Por Ehret, Georg B., Caulfield, Mark J.
Publicado em 2013

SNPs and Other Features as They Predispose to Complex Disease: Genome-Wide Predictive Analysis of a Quantitative Phenotype for Hypertension

Por Won, Joong-Ho, Ehret, Georg, Chakravarti, Aravinda, Olshen, Richard A.
Publicado em 2011

Follow-up of a major linkage peak on chromosome 1 reveals suggestive QTLs associated with essential hypertension: GenNet study

Por Ehret, Georg B, O'Connor, Ashley A, Weder, Alan, Cooper, Richard S, Chakravarti, Aravinda
Publicado em 2009

A Multi-SNP Locus-Association Method Reveals a Substantial Fraction of the Missing Heritability

Por Ehret, Georg B., Lamparter, David, Hoggart, Clive J., Whittaker, John C., Beckmann, Jacques S., Kutalik, Zoltán
Publicado em 2012

Molecular pathways associated with blood pressure and hexadecanedioate levels

Por Menni, Cristina, Metrustry, Sarah J., Ehret, Georg, Dominiczak, Anna F., Chowienczyk, Phil, Spector, Tim D., Padmanabhan, Sandosh, Valdes, Ana M.
Publicado no PLoS One (2017)

Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation

Por Hoffmann, Thomas J., Ehret, Georg B., Nandakumar, Priyanka, Ranatunga, Dilrini, Schaefer, Catherine, Kwok, Pui-Yan, Iribarren, Carlos, Chakravarti, Aravinda, Risch, Neil
Publicado no Nat Genet (2016)

Protocol of the Swiss Longitudinal Cohort Study (SWICOS) in rural Switzerland

Por Schoenenberger, Andreas W, Muggli, Franco, Parati, Gianfranco, Gallino, Augusto, Ehret, Georg, Suter, Paolo M, Schoenenberger-Berzins, Renate, Resink, Therese J, Erne, Paul
Publicado no BMJ Open (2016)

Replication of the Wellcome Trust genome-wide association study of essential hypertension: The Family Blood Pressure Program

Por Ehret, Georg B, Morrison, Alanna C, O’Connor, Ashley A, Grove, Megan L, Baird, Lisa, Schwander, Karen, Weder, Alan, Cooper, Richard S, Rao, DC, Hunt, Steven C, Boerwinkle, Eric, Chakravarti, Aravinda
Publicado em 2008

Sequence Analysis of Six Blood Pressure Candidate Regions in 4,178 Individuals: The Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Targeted Sequencing Study

Por Morrison, Alanna C., Bis, Joshua C., Hwang, Shih-Jen, Ehret, Georg B., Lumley, Thomas, Rice, Kenneth, Muzny, Donna, Gibbs, Richard A., Boerwinkle, Eric, Psaty, Bruce M., Chakravarti, Aravinda, Levy, Daniel
Publicado em 2014

Next-Generation Sequencing of Human Mitochondrial Reference Genomes Uncovers High Heteroplasmy Frequency

Por Sosa, Maria Ximena, Sivakumar, I. K. Ashok, Maragh, Samantha, Veeramachaneni, Vamsi, Hariharan, Ramesh, Parulekar, Minothi, Fredrikson, Karin M., Harkins, Timothy T., Lin, Jeffrey, Feldman, Andrew B., Tata, Pramila, Ehret, Georg B., Chakravarti, Aravinda
Publicado em 2012

Integrated Computational and Experimental Analysis of the Neuroendocrine Transcriptome in Genetic Hypertension Identifies Novel Control Points for the Cardio-Metabolic Syndrome

Por Friese, Ryan S., Ye, Chun, Nievergelt, Caroline M., Schork, Andrew J., Mahapatra, Nitish R., Rao, Fangwen, Napolitan, Philip S., Waalen, Jill, Ehret, Georg B., Munroe, Patricia B., Schmid-Schönbein, Geert W., Eskin, Eleazar, O’Connor, Daniel T.
Publicado em 2012

Copeptin Is Associated with Kidney Length, Renal Function, and Prevalence of Simple Cysts in a Population-Based Study

Por Ponte, Belen, Pruijm, Menno, Ackermann, Daniel, Vuistiner, Philippe, Guessous, Idris, Ehret, Georg, Alwan, Heba, Youhanna, Sonia, Paccaud, Fred, Mohaupt, Markus, Péchère-Bertschi, Antoinette, Vogt, Bruno, Burnier, Michel, Martin, Pierre-Yves, Devuyst, Olivier, Bochud, Murielle
Publicado no J Am Soc Nephrol (2015)

The role of GRIP1 and ephrin B3 in blood pressure control and vascular smooth muscle cell contractility

Por Wang, Yujia, Wu, Zenghui, Luo, Hongyu, Peng, Junzheng, Raelson, John, Ehret, Georg B., Munroe, Patricia B., Stoyanova, Ekatherina, Qin, Zhao, Cloutier, Guy, Bradley, W. Edward, Wu, Tao, Shen, Jian-Zhong, Hu, Shenjiang, Wu, Jiangping
Publicado no Sci Rep (2016)

Effects of Rare and Common Blood Pressure Gene Variants on Essential Hypertension: Results from the FBPP, CLUE and ARIC Studies

Por Nguyen, Khanh-Dung H., Pihur, Vasyl, Ganesh, Santhi K., Rakha, Ankit, Cooper, Richard S., Hunt, Steven C., Freedman, Barry I., Coresh, Joe, Kao, Wen H. L., Morrison, Alanna C., Boerwinkle, Eric, Ehret, Georg B., Chakravarti, Aravinda
Publicado em 2012

CYP17A1 Enzyme Activity Is Linked to Ambulatory Blood Pressure in a Family-Based Population Study

Por Ackermann, Daniel, Pruijm, Menno, Ponte, Belen, Guessous, Idris, Ehret, Georg, Escher, Geneviève, Dick, Bernhard, Al-Alwan, Heba, Vuistiner, Philippe, Paccaud, Fred, Burnier, Michel, Péchère-Bertschi, Antoinette, Martin, Pierre-Yves, Vogt, Bruno, Mohaupt, Markus, Bochud, Murielle
Publicado no Am J Hypertens (2016)

An ancestral variant of Secretogranin II confers regulation by PHOX2 transcription factors and association with hypertension

Por Wen, Gen, Wessel, Jennifer, Zhou, Weidong, Ehret, Georg B., Rao, Fangwen, Stridsberg, Mats, Mahata, Sushil K., Gent, Peter M., Das, Madhusudan, Cooper, Richard S., Chakravarti, Aravinda, Zhou, Huilin, Schork, Nicholas J., O’Connor, Daniel T., Hamilton, Bruce A.
Publicado em 2007

Relation of 24-hour urinary caffeine and caffeine metabolite excretions with self-reported consumption of coffee and other caffeinated beverages in the general population

Por Petrovic, Dusan, Estoppey Younes, Sandrine, Pruijm, Menno, Ponte, Belén, Ackermann, Daniel, Ehret, Georg, Ansermot, Nicolas, Mohaupt, Markus, Paccaud, Fred, Vogt, Bruno, Pechère-Bertschi, Antoinette, Martin, Pierre-Yves, Burnier, Michel, Eap, Chin B., Bochud, Murielle, Guessous, Idris
Publicado no Nutr Metab (Lond) (2016)

Associations of Urinary Uromodulin with Clinical Characteristics and Markers of Tubular Function in the General Population

Por Pruijm, Menno, Ponte, Belen, Ackermann, Daniel, Paccaud, Fred, Guessous, Idris, Ehret, Georg, Pechère-Bertschi, Antoinette, Vogt, Bruno, Mohaupt, Markus G., Martin, Pierre-Yves, Youhanna, Sonia C., Nägele, Nadine, Vollenweider, Peter, Waeber, Gérard, Burnier, Michel, Devuyst, Olivier, Bochud, Murielle
Publicado no Clin J Am Soc Nephrol (2016)