Genes for common diseases

Por Caulfield, Mark J
Publicado em 2001

Genes for blood pressure: an opportunity to understand hypertension

Por Ehret, Georg B., Caulfield, Mark J.
Publicado em 2013

Predicting deleterious nsSNPs: an analysis of sequence and structural attributes

Por Saqi Mansoor AS, Caulfield Mark J, Munroe Patricia B, Dobson Richard J
Publicado em 2006-04-01

Predicting deleterious nsSNPs: an analysis of sequence and structural attributes

Por Dobson, Richard J, Munroe, Patricia B, Caulfield, Mark J, Saqi, Mansoor AS
Publicado em 2006

Information capture using SNPs from HapMap and whole-genome chips differs in a sample of inflammatory and cardiovascular gene-centric regions from genome-wide estimates

Por Wallace, Chris, Dobson, Richard J., Munroe, Patricia B., Caulfield, Mark J.
Publicado em 2007

Dietary nitrate provides sustained blood pressure lowering in hypertensive patients: a randomized, phase 2, double-blind, placebo-controlled study

Por Kapil, Vikas, Khambata, Rayomand S, Robertson, Amy, Caulfield, Mark J, Ahluwalia, Amrita
Publicado no Hypertension (2014)

A blood pressure-associated variant of the SLC39A8 gene influences cellular cadmium accumulation and toxicity

Por Zhang, Ruoxin, Witkowska, Kate, Afonso Guerra-Assunção, José, Ren, Meixia, Ng, Fu Liang, Mauro, Claudio, Tucker, Arthur T., Caulfield, Mark J., Ye, Shu
Publicado no Hum Mol Genet (2016)

Functional analyses of coronary artery disease associated variation on chromosome 9p21 in vascular smooth muscle cells

Por Motterle, Anna, Pu, Xiangyuan, Wood, Harriet, Xiao, Qingzhong, Gor, Shivani, Liang Ng, Fu, Chan, Kenneth, Cross, Frank, Shohreh, Beski, Poston, Robin N., Tucker, Arthur T., Caulfield, Mark J., Ye, Shu
Publicado em 2012

Blood pressure and incidence of twelve cardiovascular diseases: lifetime risks, healthy life-years lost, and age-specific associations in 1·25 million people

Por Rapsomaniki, Eleni, Timmis, Adam, George, Julie, Pujades-Rodriguez, Mar, Shah, Anoop D, Denaxas, Spiros, White, Ian R, Caulfield, Mark J, Deanfield, John E, Smeeth, Liam, Williams, Bryan, Hingorani, Aroon, Hemingway, Harry
Publicado em 2014

Randomised, double-blind, placebo-controlled study investigating the effects of inorganic nitrate on vascular function, platelet reactivity and restenosis in stable angina: protoco...

Por Rathod, Krishnaraj S, Jones, Daniel A, Van-Eijl, T J A, Tsang, Hilda, Warren, Helen, Hamshere, Stephen M, Kapil, Vikas, Jain, Ajay K, Deaner, Andrew, Poulter, Neil, Caulfield, Mark J, Mathur, Anthony, Ahluwalia, Amrita
Publicado no BMJ Open (2016)

Extracellular volume quantification in isolated hypertension - changes at the detectable limits?

Por Treibel, Thomas A., Zemrak, Filip, Sado, Daniel M., Banypersad, Sanjay M., White, Steven K., Maestrini, Viviana, Barison, Andrea, Patel, Vimal, Herrey, Anna S., Davies, Ceri, Caulfield, Mark J., Petersen, Steffen E., Moon, James C.
Publicado no J Cardiovasc Magn Reson (2015)

Spironolactone versus placebo, bisoprolol, and doxazosin to determine the optimal treatment for drug-resistant hypertension (PATHWAY-2): a randomised, double-blind, crossover trial

Por Williams, Bryan, MacDonald, Thomas M, Morant, Steve, Webb, David J, Sever, Peter, McInnes, Gordon, Ford, Ian, Cruickshank, J Kennedy, Caulfield, Mark J, Salsbury, Jackie, Mackenzie, Isla, Padmanabhan, Sandosh, Brown, Morris J
Publicado no Lancet (2015)

Effect of amiloride, or amiloride plus hydrochlorothiazide, versus hydrochlorothiazide on glucose tolerance and blood pressure (PATHWAY-3): a parallel-group, double-blind randomise...

Por Brown, Morris J, Williams, Bryan, Morant, Steve V, Webb, David J, Caulfield, Mark J, Cruickshank, J Kennedy, Ford, Ian, McInnes, Gordon, Sever, Peter, Salsbury, Jackie, Mackenzie, Isla S, Padmanabhan, Sandosh, MacDonald, Thomas M
Publicado no Lancet Diabetes Endocrinol (2016)

Novel polymorphic AluYb8 insertion in the WNK1 gene is associated with blood pressure variation in Europeans

Por Putku, Margus, Kepp, Katrin, Org, Elin, Sõber, Siim, Comas, David, Viigimaa, Margus, Veldre, Gudrun, Juhanson, Peeter, Hallast, Pille, Tõnisson, Neeme, Shaw-Hawkins, Sue, Caulfield, Mark J, Khusnutdinova, Elza, Kožich, Viktor, Munroe, Patricia B, Laan, Maris
Publicado em 2011

Joint UK societies’ 2014 consensus statement on renal denervation for resistant hypertension

Por Lobo, Melvin D, de Belder, Mark A, Cleveland, Trevor, Collier, David, Dasgupta, Indranil, Deanfield, John, Kapil, Vikas, Knight, Charles, Matson, Matthew, Moss, Jonathan, Paton, Julian F R, Poulter, Neil, Simpson, Iain, Williams, Bryan, Caulfield, Mark J
Publicado no Heart (2015)

Coronary-Heart-Disease-Associated Genetic Variant at the COL4A1/COL4A2 Locus Affects COL4A1/COL4A2 Expression, Vascular Cell Survival, Atherosclerotic Plaque Stability and Risk of...

Por Yang, Wei, Ng, Fu Liang, Chan, Kenneth, Pu, Xiangyuan, Poston, Robin N., Ren, Meixia, An, Weiwei, Zhang, Ruoxin, Wu, Jingchun, Yan, Shunying, Situ, Haiteng, He, Xinjie, Chen, Yequn, Tan, Xuerui, Xiao, Qingzhong, Tucker, Arthur T., Caulfield, Mark J., Ye, Shu
Publicado no PLoS Genet (2016)

ADAMTS7 Cleavage and Vascular Smooth Muscle Cell Migration Is Affected by a Coronary-Artery-Disease-Associated Variant

Por Pu, Xiangyuan, Xiao, Qingzhong, Kiechl, Stefan, Chan, Kenneth, Ng, Fu Liang, Gor, Shivani, Poston, Robin N., Fang, Changcun, Patel, Ashish, Senver, Ece C., Shaw-Hawkins, Sue, Willeit, Johann, Liu, Chuanju, Zhu, Jianhua, Tucker, Arthur T., Xu, Qingbo, Caulfield, Mark J., Ye, Shu
Publicado em 2013

COMMON POLYMORPHISMS AT THE CYP17A1 LOCUS ASSOCIATE WITH STEROID PHENOTYPE: SUPPORT FOR BLOOD PRESSURE GWAS SIGNALS AT THIS LOCUS

Por Diver, Louise A., MacKenzie, Scott M., Fraser, Robert, McManus, Frances, Freel, E. Marie, Alvarez-Madrazo, Samantha, McClure, John D., Friel, Elaine C., Hanley, Neil A., Dominiczak, Anna F., Caulfield, Mark J., Munroe, Patricia B., Connell, John M., Davies, Eleanor
Publicado no Hypertension (2016)

Linkage Analysis Using Co-Phenotypes in the BRIGHT Study Reveals Novel Potential Susceptibility Loci for Hypertension

Por Wallace, Chris, Xue, Ming-Zhan, Newhouse, Stephen J., Marçano, Ana Carolina B., Onipinla, Abiodun K., Burke, Beverley, Gungadoo, Johannie, Dobson, Richard J., Brown, Morris, Connell, John M., Dominiczak, Anna, Lathrop, G. Mark, Webster, John, Farrall, Martin, Mein, Charles, Samani, Nilesh J., Caulfield, Mark J., Clayton, David G., Munroe, Patricia B.
Publicado em 2006

Genome-wide Association Study Identifies Genes for Biomarkers of Cardiovascular Disease: Serum Urate and Dyslipidemia

Por Wallace, Chris, Newhouse, Stephen J., Braund, Peter, Zhang, Feng, Tobin, Martin, Falchi, Mario, Ahmadi, Kourosh, Dobson, Richard J., Marçano, Ana Carolina B., Hajat, Cother, Burton, Paul, Deloukas, Panagiotis, Brown, Morris, Connell, John M., Dominiczak, Anna, Lathrop, G. Mark, Webster, John, Farrall, Martin, Spector, Tim, Samani, Nilesh J., Caulfield, Mark J., Munroe, Patricia B.
Publicado em 2008