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Novel polymorphic AluYb8 insertion in the WNK1 gene is associated with blood pressure variation in Europeans
Mutations in WNK1 and WNK4 cause familial hypertension, the Gordon syndrome. WNK1 and WNK4 conserved noncoding regions were targeted to polymorphism screening using DHPLC and DGGE. The scan identified an undescribed polymorphic AluYb8 insertion in WNK1 intron 10. Screening in primates revealed that...
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| Main Authors: | , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Wiley Subscription Services, Inc., A Wiley Company
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3298642/ https://ncbi.nlm.nih.gov/pubmed/21520334 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.21508 |
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