Predicting deleterious nsSNPs: an analysis of sequence and structural attributes

BACKGROUND: There has been an explosion in the number of single nucleotide polymorphisms (SNPs) within public databases. In this study we focused on non-synonymous protein coding single nucleotide polymorphisms (nsSNPs), some associated with disease and others which are thought to be neutral. We des...

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Autori principali: Dobson, Richard J, Munroe, Patricia B, Caulfield, Mark J, Saqi, Mansoor AS
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2006
Soggetti:
Methodology Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489951/
https://ncbi.nlm.nih.gov/pubmed/16630345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-7-217
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