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In-Silico Computing of the Most Deleterious nsSNPs in HBA1 Gene
BACKGROUND: α-Thalassemia (α-thal) is a genetic disorder caused by the substitution of single amino acid or large deletions in the HBA1 and/or HBA2 genes. METHOD: Using modern bioinformatics tools as a systematic in-silico approach to predict the deleterious SNPs in the HBA1 gene and its significant...
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| Published in: | PLoS One |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Public Library of Science
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4733110/ https://ncbi.nlm.nih.gov/pubmed/26824843 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0147702 |
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