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In-Silico Computing of the Most Deleterious nsSNPs in HBA1 Gene

BACKGROUND: α-Thalassemia (α-thal) is a genetic disorder caused by the substitution of single amino acid or large deletions in the HBA1 and/or HBA2 genes. METHOD: Using modern bioinformatics tools as a systematic in-silico approach to predict the deleterious SNPs in the HBA1 gene and its significant...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: AbdulAzeez, Sayed, Borgio, J. Francis
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4733110/
https://ncbi.nlm.nih.gov/pubmed/26824843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0147702
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