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CYP17A1 Enzyme Activity Is Linked to Ambulatory Blood Pressure in a Family-Based Population Study

BACKGROUND: Genome-wide association studies have linked CYP17A1 coding for the steroid hormone synthesizing enzyme 17α-hydroxylase (CYP17A1) to blood pressure (BP). We hypothesized that the genetic signal may translate into a correlation of ambulatory BP (ABP) with apparent CYP17A1 activity in a fam...

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Detalhes bibliográficos
Publicado no:Am J Hypertens
Main Authors: Ackermann, Daniel, Pruijm, Menno, Ponte, Belen, Guessous, Idris, Ehret, Georg, Escher, Geneviève, Dick, Bernhard, Al-Alwan, Heba, Vuistiner, Philippe, Paccaud, Fred, Burnier, Michel, Péchère-Bertschi, Antoinette, Martin, Pierre-Yves, Vogt, Bruno, Mohaupt, Markus, Bochud, Murielle
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4886492/
https://ncbi.nlm.nih.gov/pubmed/26297028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ajh/hpv138
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