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Using Systems Approaches to Address Challenges for Clinical Implementation of Pharmacogenomics

Many genetic variants have been shown to affect drug response through changes in drug efficacy and likelihood of adverse effects. Much of pharmacogenomic science has focused on discovering and clinically implementing single gene variants with large effect sizes. Given the increasing complexities of...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Karnes, Jason H, Van Driest, Sara, Bowton, Erica A, Weeke, Peter E, Mosley, Jonathan D, Peterson, Josh F, Denny, Joshua C, Roden, Dan M
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944797/
https://ncbi.nlm.nih.gov/pubmed/24319008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/wsbm.1255
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