A genome-wide association study of heparin-induced thrombocytopenia using an electronic medical record

Heparin-induced thrombocytopenia (HIT) is an unpredictable, potentially catastrophic adverse effect of heparin treatment resulting from an immune response to platelet factor 4 (PF4)/heparin complexes. No genome-wide evaluations have been performed to identify potential genetic influences on HIT. Her...

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Vydáno v:Thromb Haemost
Hlavní autoři: Karnes, Jason H, Cronin, Robert M, Rollin, Jerome, Teumer, Alexander, Pouplard, Claire, Shaffer, Christian M, Blanquicett, Carmelo, Bowton, Erica A, Cowan, James D, Mosley, Jonathan D, Van Driest, Sara L, Weeke, Peter E, Wells, Quinn S, Bakchoul, Tamam, Denny, Joshua C, Greinacher, Andreas, Gruel, Yves, Roden, Dan M
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4433536/
https://ncbi.nlm.nih.gov/pubmed/25503805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1160/TH14-08-0670
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