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A genome-wide association study of heparin-induced thrombocytopenia using an electronic medical record

Heparin-induced thrombocytopenia (HIT) is an unpredictable, potentially catastrophic adverse effect of heparin treatment resulting from an immune response to platelet factor 4 (PF4)/heparin complexes. No genome-wide evaluations have been performed to identify potential genetic influences on HIT. Her...

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Dettagli Bibliografici
Pubblicato in:Thromb Haemost
Autori principali: Karnes, Jason H, Cronin, Robert M, Rollin, Jerome, Teumer, Alexander, Pouplard, Claire, Shaffer, Christian M, Blanquicett, Carmelo, Bowton, Erica A, Cowan, James D, Mosley, Jonathan D, Van Driest, Sara L, Weeke, Peter E, Wells, Quinn S, Bakchoul, Tamam, Denny, Joshua C, Greinacher, Andreas, Gruel, Yves, Roden, Dan M
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4433536/
https://ncbi.nlm.nih.gov/pubmed/25503805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1160/TH14-08-0670
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