Influence of HLA alleles and KIR types on Heparin-Induced Thrombocytopenia

OBJECTIVES: Variation in human leukocyte antigen (HLA) genes is now used to prevent immune-mediated adverse drug reactions. Combinations of HLA alleles and killer cell immunoglobulin-like receptors (KIR) are associated with multiple autoimmune diseases and infections. Heparin-induced thrombocytopeni...

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Detalhes bibliográficos
Publicado no:Pharmacotherapy
Main Authors: Karnes, Jason H, Shaffer, Christian M, Cronin, Robert, Bastarache, Lisa, Gaudieri, Silvana, James, Ian, Pavlos, Rebecca, Steiner, Heidi, Mosley, Jonathan D, Mallal, Simon, Denny, Joshua C, Phillips, Elizabeth J, Roden, Dan M
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5600645/
https://ncbi.nlm.nih.gov/pubmed/28688202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/phar.1983
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